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CompletedNCT04555395Updated Sep 18, 2020

The Differences Between Gonadal and Extra-gonadal Malignant Teratomas

An observational study in SEER Database, sponsored by Shanghai 10th People's Hospital. Completed. Per ClinicalTrials.gov, last updated 2020-09-18.

Sponsored by Shanghai 10th People's Hospital · Observational

Study type
Observational
Model
Case-crossover
Time perspective
Retrospective
Enrollment
3,799
Sex
All
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Study summary

A tumor comprising of different types of tissues (such as hair, muscle, bone, etc.) is known as a teratoma. It is a type of germ cell (cells that make sperm or eggs) tumor. When these germ cells have rapid cancerous growth, then such a teratoma is called a malignant teratoma. We have studied the differences between gonadal and extra-gonadal malignant teratomas and the effects of chemotherapy in both genders.

Methods: The samples of 3799 male and 1832 female patients with malignant teratoma samples, between the ages of 1 and 85+ years, were selected from the years 1973 to 2014. Trends in incidence, estimated prevalence, incidence rates, and frequency were calculated in gonadal and extra-gonadal tumors with age adjustment. The fiveyear observed, expected, and relative survival rates were analyzed to study the prognosis.

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Conditions studied

  • SEER Database

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In context

Teratoma

41 studies on the registry are indexed under Teratoma; 7 are open to participants now.

This study's enrollment of 3,799 is above the median of 247 across 13 observational studies indexed under Teratoma.

Browse Teratoma studies →

Lead sponsor

Shanghai 10th People's Hospital is the lead sponsor of 167 studies on the registry; 45 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

The registry used in our study was the SEER 9 registries Custom Data (with additional treatment fields), Nov 2016 Submission (1973-2014) \< Katrina/Rita Population Adjustment> - Linked to County Attributes -Total United States, 1969-2015 Counties, National Cancer Institute, DCCPS (Division of Cancer Control and Population Sciences), Surveillance Research Program, released April 2017, based on the November 2016 submission.

Eligibility criteria

The registry used in our study was the SEER 9 registries Custom Data (with additional treatment fields), Nov 2016 Submission (1973-2014) \< Katrina/Rita Population Adjustment> - Linked to County Attributes -Total United States, 1969-2015 Counties, National Cancer Institute, DCCPS (Division of Cancer Control and Population Sciences), Surveillance Research Program, released April 2017, based on the November 2016 submission.

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Study design

Observational model
Case-crossover
Time perspective
Retrospective
Enrollment
3,799 participants (actual)
Patient registry
No

Groups and cohorts

  • gonadal

    Other: survival rates

  • extra-gonadal

    Other: survival rates

  • chemotherapy

    Other: survival rates

  • without chemotherapy

    Other: survival rates

Interventions

  • Othersurvival rates

    survival rates

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What researchers measure

Primary outcomes

  1. survival rates

    Time frame: 1973-2014

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Study locations

No study locations are listed for this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 18, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04555395
Lead sponsor
Shanghai 10th People's Hospital
Responsible party
Zhang Manna (Shanghai 10th People's Hospital, Shanghai 10th People's Hospital) — Principal investigator
First posted
Sep 18, 2020
Start date
Jan 1, 1973
Primary completion
Jan 1, 2020
Completion
Jan 1, 2020
Last update
Sep 18, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.

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