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CompletedNCT04543175Updated Sep 10, 2020

Taste Disorders and Their Relation to BMI, FFQ, and EORTC QLQ-BR23 in Breast Cancer Patients During Chemotherapy.

An observational study in Breast Cancer, Taste Disorders and Dysgeusia, sponsored by Hospital General de Mexico. Completed at 1 site in Mexico. Open to female participants aged 20 Years to 60 Years. Per ClinicalTrials.gov, last updated 2020-09-10.

Sponsored by Hospital General de Mexico · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
106
Ages
20 Years to 60 Years
Sex
Female
01

Study summary

Taste disorders in cancer patients during chemotherapy could be consider as multifactorial disease, it is related with changes of food consumption. Approximately 36-69% of the patients under chemotherapy suffer oral toxicity or dysgeusia

A prospective case- only observational study was conducted in patients of the Hospital General de México for two years. A self-reported taste survey was used, and patients scored their results in a Likert scale.

02

Conditions studied

  • Breast Cancer
  • Taste Disorders
  • Dysgeusia
  • Ageusia
  • Quality of Life
03

In context

Breast Neoplasms

14,825 studies on the registry are indexed under Breast Neoplasms; 3,319 are open to participants now.

This study's enrollment of 106 is below the median of 184 across 3,235 observational studies indexed under Breast Neoplasms.

Browse Breast Neoplasms studies →

Lead sponsor

Hospital General de Mexico is the lead sponsor of 28 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 60 Years
Sexes eligible
Female
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients of Oncology ward in Hospital General de Mexico between 20 and 60 years old with newly diagnosed breast cancer.

and chemotherapy with Doxorubicin + Cyclophosphamide (DC) or Paclitaxel + Carboplatin (PC) or Docetaxel.

Eligibility criteria

Inclusion Criteria:

  • Chemotherapy with Doxorubicin + Cyclophosphamide (DC) or Paclitaxel + Carboplatin (PC) or Docetaxel.

Exclusión Criteria:

  • No smokers Infections in oral cavity Acute respiratory diseases Gastro- oesophageal reflux disease Other types of cancer.
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
106 participants (actual)
Patient registry
No

Groups and cohorts

  • Chemotherapy breast cancer patients

    Newly diagnosed breast cancer patients (clinical stages IA, IIA, IIB, IIIA and IIIB) before and after chemotherapy with the following drugs (Doxorubicin + Cyclophosphamide (DC) or Paclitaxel + Carboplatin (PC) or Docetaxel were followed until they complete four cycles of chemotherapy.

    Other: Taste disorder´s test

Interventions

  • OtherTaste disorder´s test

    Each patient performed their own test placing three drops with a disposable dropper from each bottle into the center of the tongue for whole-mouth testing.

    Also known as: Taste disorders

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What researchers measure

Primary outcomes

  1. Prevalence of taste disorders and perception of the four basic flavors

    to assess the prevalence of taste alterations perception of the four basic flavors (sweet, salty, bitter and acidic) in newly diagnosed breast cancer patients (clinical stages IA, IIA, IIB, IIIA and IIIB) before and after chemotherapy

    Time frame: 21 days

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Study locations

1 site
  • Hospital General de México
    Mexico City, 06726, Mexico
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 10, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04543175
Lead sponsor
Hospital General de Mexico
Responsible party
Dr. Vanessa Fuchs Tarlovsky (Principal investigator, Hospital General de Mexico) — Principal investigator
First posted
Sep 10, 2020
Start date
Jan 1, 2017
Primary completion
Jan 1, 2018
Completion
Jan 1, 2019
Last update
Sep 10, 2020

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.

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