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CompletedNCT04493268Updated Jul 30, 2020

HYPONATREMIA IN COVID-19 PATIENTS

An observational study in Hyponatremia, Covid19 and Corona Virus Infection, sponsored by Hospital Nacional Profesor Alejandro Posadas. Completed at 1 site in Argentina. Open to participants aged 1 Month to 100 Years. Per ClinicalTrials.gov, last updated 2020-07-30.

Sponsored by Hospital Nacional Profesor Alejandro Posadas · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
250
Ages
1 Month to 100 Years
Sex
All
01

Study summary

SYSTEMIC INFLAMMATION HAS BEEN ASSOCIATED WITH SEVERE COVID-19. HYPONATREMIA CAN RESULT FROM INFLAMMATION DUE TO NON-OSMOTIC STIMULI FOR VASOPRESSIN PRODUCTION. IN THIS PROSPECTIVE COHORT STUDY WE ANALIZED DATA FROM PATIENTS WITH COVID-19 AND THE ASOCIATION WITH HYPONATREMIA AND CLINICAL OUTCOMES.

02

Conditions studied

  • Hyponatremia
  • Covid19
  • Corona Virus Infection

Keywords

  • INFLAMMATION
  • COVID
  • CORONA
03

In context

COVID-19

7,640 studies on the registry are indexed under COVID-19; 488 are open to participants now.

This study's enrollment of 250 is close to the median of 261 across 3,136 observational studies indexed under COVID-19.

Browse COVID-19 studies →

Lead sponsor

Hospital Nacional Profesor Alejandro Posadas is the lead sponsor of 8 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
1 Month to 100 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

GENERAL POPULATION

Inclusion criteria

  • PATIENTS WITH SARS-CoV-2 INFECTION CONFIRMED BY PCR OF NASOPHARYNGEAL SWABS.

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
250 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. MORTALITY

    HYPONATREMIA AND MORTALITY

    Time frame: 30 DAYS

Secondary outcomes

  1. ICU HOSPITALIZATION

    HYPONATREMIA AND ICU HOSPITALIZATION

    Time frame: 30 DAYS

07

Study locations

1 site
  • Hospital Posadas
    Buenos Aires, 1684, Argentina
08

References and documents

Publications

  • Ayus JC, Negri AL, Moritz ML, Lee KM, Caputo D, Borda ME, Go AS, Eghi C. Hyponatremia, Inflammation at Admission, and Mortality in Hospitalized COVID-19 Patients: A Prospective Cohort Study. Front Med (Lausanne). 2021 Dec 2;8:748364. doi: 10.3389/fmed.2021.748364. eCollection 2021. PubMed 34926496 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 30, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04493268
Lead sponsor
Hospital Nacional Profesor Alejandro Posadas
Responsible party
Ladislao Diaz Ballve (GRADUATE IN KINESIOLOGY, Hospital Nacional Profesor Alejandro Posadas) — Principal investigator
First posted
Jul 30, 2020
Start date
Mar 7, 2020
Primary completion
Jul 20, 2020
Completion
Jul 21, 2020
Last update
Jul 30, 2020

Study contacts

CARLOS EGHI, physician
principal investigator · University of Buenos Aires

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2020. You cannot join it, but the record below documents what was studied.

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