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Hyponatremia clinical trials

The registry lists 164 studies for Hyponatremia across more than 10 countries. 16 are recruiting or about to start. 118 of them are mainly about Hyponatremia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.

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Status

Completed
101
Status unknown
21
Terminated
18
Recruiting
14
Withdrawn
5
Active, not recruiting
3

Phase

Phase 3
32
Phase 4
18
Phase 2
14
Phase 1
4
Early Phase 1
2

Where

United States
40
Germany
24
Switzerland
17
Spain
14
France
14
Canada
13

Who runs them

University Hospital, Basel, Switzerland (13) · Cumberland Pharmaceuticals (9) · Otsuka Pharmaceutical Development & Commercialization, Inc. (8) · Sanofi (6) · University of Cologne (6) · Korea Otsuka Pharmaceutical Co., Ltd. (3) · Otsuka Pharmaceutical Europe Ltd (3) · Hospital Italiano de Buenos Aires (3)

What is being tested here

Drugs under test in Hyponatremia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Sodium Chloride126
Urea104
Glucose112
Deamino Arginine Vasopressin111
Tolvaptan01019
Conivaptan0711
Satavaptan046
Empagliflozin034
Lixivaptan022
Midodrine001

Coming up

1phase 3 study under way
4studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4

Who these studies take

Of the 14 Hyponatremia studies recruiting now, 13 (93%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (7%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 14
AgeWomenMen
101 (7%)1 (7%)
1814 (100%)14 (100%)
3014 (100%)14 (100%)
4014 (100%)14 (100%)
5014 (100%)14 (100%)
6514 (100%)14 (100%)
7514 (100%)14 (100%)
8514 (100%)14 (100%)

Across all 164 studies, recruiting or not: 21% stop at 75 or younger and 17% at 65; 17% take children; 2% are for women only and 3% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Hyponatremia studies take

Of 24 interventional studies with no phase under Hyponatremia, half reached primary completion within 24 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase24 mo12–48 · 24 studies——
Observational32 mo12–59 · 18 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 164. Browse all 164 → or search them.