An observational study in Sport Injury and Osteoarthritis, Knee, sponsored by Peking University Third Hospital. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2020-07-08.
Sponsored by Peking University Third Hospital · Observational
The current common clinical methods cannot truly reflect the biomechanical status of the knee joint. Based on the foot-knee coupling mechanism, the simple and practical dynamic gait touch information provided by the 3D force platform are closely related to the knee biomechanics. The purpose of this study is to investigate the disease feature recognition, computer-aided diagnosis and rehabilitation assessment based on the gait touch information related to lower limb injuries.
Background:
The current common clinical methods cannot truly reflect the biomechanical status of the knee joint. The three-dimensional gait analysis is the gold standard, but it is difficult to apply clinically. There is an urgent need for a clinically practical method to quantitatively evaluate the biomechanics of the knee joint under dynamic weight bearing.
Methods:
50 healthy volunteers, 450 sports injuries patients (including hip, knee, and ankle joint diseases) and 50 patients with degenerative osteoarthritis were recruited.
55 passive reflective markers were placed bilaterally on the body. Lower extremity kinematics and dynamic plantar pressure during walking, jogging were collected.
Outcome evaluation indicators and statistical methods: The following indicators use repeated measurement two-factor analysis of variance: the left and right sides, different rehabilitation times are used as repeated measurement variables, to analyze the biomechanical changes of the lower limb joint biomechanics and gait touch information. A variety of machine learning methods (such as PCA, SVM, CNN, etc.) are used to analyze, and select the appropriate algorithm and parameters according to the learning effect. Finally, this study will establish a machine learning models for computer-aided diagnosis, treatment, and rehabilitation assessment.
3,302 studies on the registry are indexed under Osteoarthritis, Knee; 608 are open to participants now.
This study's planned enrollment of 550 is above the median of 100 across 472 observational studies indexed under Osteoarthritis, Knee.
Browse Osteoarthritis, Knee studies →Peking University Third Hospital is the lead sponsor of 735 studies on the registry; 262 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion: one healthy control group: healthy volunteers; and patients with a certain sports injury (soft tissue injury or degenerative osteoarthritis) of a joint of the lower limb (hip or knee or ankle or foot).
Exclusion: Cognitive impairment or other injuries affecting movement performance.
Exclusion Criteria:
According to the previous clinical diagnosis, volunteers who has never suffered the lower extremity sports injuries.
Other: no intervention
According to the previous clinical diagnosis, patients who has suffered the sports injuries(including hip, knee, and ankle joint diseases).
Other: no intervention
According to the previous clinical diagnosis, patients who has suffered the degenerative osteoarthritis.
Other: no intervention
This is an observation study, with no intervention
walking speed
Three-dimensional gait analysis system and plantar pressure were used during walking.
Time frame: On the day of enrollment.
ground reaction force
Three-dimensional gait analysis system and plantar pressure were used during walking.
Time frame: On the day of enrollment.
knee flexion angle
Three-dimensional gait analysis system and plantar pressure were used during walking.
Time frame: On the day of enrollment.
the moment of knee extension in the gait cycle
Three-dimensional gait analysis system and plantar pressure were used during walking.
Time frame: On the day of enrollment.
The International Knee Documentation Committee (IKDC) score
The International Knee Documentation Committee (IKDC) score was used to evaluate the knee health.The patients completed score by themselves. The lowest score is 0 and the highest score is 100.
Time frame: On the day of enrollment.
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Jun 2020. You cannot join it, but the record below documents what was studied.
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Peking University Third Hospital