An interventional study of Auditory perception tasks in healthy participants in Healthy Volunteers, sponsored by Hospices Civils de Lyon. Completed at 1 site in France. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-20.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Basic science
For humans and other animals, predicting the timing of sensory events is essential for their daily behavior. Importantly, natural sensory stimulation (such as movements, music, or speech) can present temporal regularities allowing for temporal prediction of incoming sensory information. For instance, individuals can easily predict in time the next step of a walker, or the next beat of a song based on the rhythm. The phenomenon of temporal prediction has for now only been investigated experimentally in deterministic scenarios, i.e. when the duration between two sensory events is fixed, or when stimuli present a regular beat. The objective of this project is to understand how we process more natural, hence more complex forms of temporal regularities, and how individuals make inferences on the timing of sensory events based on past temporal statistics of sensory information. This is particularly important for speech processing, considering that speech is an acoustic signal that is known to possess some form of temporal regularity, and yet is not purely rhythmic nor does have a deterministic temporal structure. Temporal regularities are specific to each spoken language, and both native and non-native language listeners are known to use temporal acoustic cues during speech listening. This affects speech comprehension and has a strong impact during language learning. Hence, understanding the processing of temporal regularities in speech can help improve language abilities in first and second language learners.
The project is composed of four experiments. The first behavioral experiment will investigate how auditory perception is affected by the temporal statistics of past sensory information using artificial stimuli. The second axis will investigate the neural mechanisms underlying auditory timing processing with electroencephalography (EEG). The last Magnetoencephalography (MEG, experiment 3) and EG (rxperiement 4) experiment will test the role of temporal statistics in an ecological setting, namely speech listening. The project will thus provide strong theoretical advances as it will give new insights on brain mechanisms for the processing of complex temporal information in audition and speech, and their role in language comprehension. It will also provide methodological advances. Specifically, the project will contribute to the development and validation of cutting-edge methods in MEG. Namely, it will aim at creating new tools to investigate the neural correlates of auditory and speech processing with an unprecedented temporal and spatial resolution.
205 studies on the registry are indexed under Speech; 80 are open to participants now.
This study's enrollment of 264 is above the median of 52 across 141 interventional studies indexed under Speech.
Browse Speech studies →Hospices Civils de Lyon is the lead sponsor of 1,866 studies on the registry; 448 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
For all experiments:
Additionally, for experiments 2,3 and 4 :
- Right handed
Additionally, for experiment 3 and 4:
- French as native language
Exclusion Criteria:
For All Experiments:
Additionally, for experiment 2,3 and 4 :
Additionally, for experiment 3 and 4:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
All participants signed up for experiment 1, 2, 3 or 4 complete the same protocol (1 study arm) with an intent for intra-subject correlational analyses
Other: Auditory perception tasks in healthy participants
The participants complete auditory perception tasks while EEG, and MEG record brain signals (primary outcome measure). The tasks acquire behavioral responses with button presses (secondary outcome measure). All analyses are intra-subject (no analyses are between-subject).
Stimulus-Brain (EEG) Coherence in the delta-theta range (1 Hz - 8 Hz)
Time frame: at max 90 days
Amplitude of EEG evoked responses to the target stimuli
Time frame: at max 90 days
Stimulus-Brain (MEG) Coherence in the delta-theta range (1 Hz - 8 Hz)
Time frame: at max 90 days
Amplitude of MEG evoked responses to the target stimuli
Time frame: at max 90 days
Percentage of correct responses
The secondary outcome measures will be recorded in all experiments
Time frame: at max 90 days
Response Times
The secondary outcome measures will be recorded in all experiments
Time frame: at max 90 days
Ran from Feb 2021 to primary completion in Mar 2026, 60 months.
Of 85 non-industry interventional studies with no phase under Speech, half reached primary completion within 45 months of starting (the median), counting those still running; a quarter within 14 and three quarters within 65. This study's 60 months is above that.
Counting every sponsor, half of 90 studies reached it within 45 months; a quarter within 15 and three quarters within 65.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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