An observational study in Acute Ichemic Stroke and Brain Ischemia, sponsored by University Hospital, Montpellier. Recruiting at 1 site in France. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2024-05-29.
Sponsored by University Hospital, Montpellier · Observational
Analysis of peri clot blood collected at the acute phase of stroke in order to understand physiopathological mechanisms involved in the cerebrovascular damage
It has been shown that immune cells accumulate around the clot at the acute phase of stroke. Leukocytes and their specific chemokines and cytokines regulation may impact cerebrovascular integrity.
Patients undergoing Mechanical Thrombectomy for large vessel occclusion with acute ischemic stroke
Exclusion criteria:
Patients undergoing Mechanical Thrombectomy for large vessel occclusion with acute ischemic stroke
Other: Analysis of the clot
Blood sampling at the site of intracranial occlusion during Mechanical Thrombectomy
Metalloproteinase 9 quantification
Time frame: 60 months
Metalloproteinase 2 quantification
Time frame: 60 months
Cytokines levels
Proteomic analysis of cytokines IL-1β, TNF-α, IL-6
Time frame: 60 months
Plan to share: No
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University Hospital, Montpellier