An observational study in Multiple Sclerosis, sponsored by Charles University, Czech Republic. Recruiting at 3 sites in Czechia. Open to participants aged 20 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-06.
Sponsored by Charles University, Czech Republic · Observational
Early diagnosis is a key factor for effective treatment of multiple sclerosis. Accelerometer and gyroscope measurement of tremor could screen potential motor control dysfunction and predict a risk for development of multiple sclerosis.
The aim of this study is to test whether specially developed accelerometer and gyroscope can differentiate pattern of resting postural tremor in healthy and people with multiple sclerosis.
Spectral analysis and the correlation of the average signal spectra will be computed. Moreover, categorization based on the tremor component according to the maximum likelihood estimation will be done.
3,264 studies on the registry are indexed under Multiple Sclerosis; 659 are open to participants now.
This study's planned enrollment of 30 is below the median of 100 across 970 observational studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →Charles University, Czech Republic is the lead sponsor of 228 studies on the registry; 76 are open to participants now.
Counted across the registry records on this site, refreshed daily.
People with MS and healthy volunteers
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Group 1:
Group 2:
Exclusion Criteria (both groups):
Patients with factors disturbing mobility (e.g. stroke, pregnancy, fractures) were excluded from the study.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
MS patients will be chosen by an independent neurologist.
Behavioral: Examination of tremor and upper hand functions
Healthy controls will be paired by age and sex with MS patients.
Behavioral: Examination of tremor and upper hand functions
Participants will be only examined. They will not undergo any intervention.
Tremor
accelerometer (1 m·s-2)
Time frame: baseline
Hand grip strength
Hand dynamometer JAMA
Time frame: baseline
Hand and arm function
Nine Hole Peg Test
Time frame: baseline
Psychomotor processing speed
Coin Rotation Task
Time frame: baseline
Plan to share: No
No publications or documents are linked to this record.
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Charles University, Czech Republic →