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Status unknownNCT04340635Updated Apr 9, 2020

Multi-center Ocular Biological Parameters Study

An observational study in Cataract, sponsored by Aier School of Ophthalmology, Central South University. Status unknown at 1 site in China. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2020-04-09.

Sponsored by Aier School of Ophthalmology, Central South University · Observational

The sponsor has not verified this record recently (last verified Apr 2020), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Other
Enrollment
20,000
Ages
50 Years and older
Sex
All
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Study summary

This study is a multi-center study, which collects data from multiple regions to obtain the general biological characteristics of the Chinese population. The formula for calculating the artificial lens power based on foreign populations is effectively modified based on the Chinese population.

Read the detailed description

①Relevant domestic studies on the biological characteristics of the eye are mainly limited to a certain city and region. Most of the studies that represent the biological characteristics of the general population in China and the differences in biological parameters at home and abroad are in the research process, or Semi-finished products.

②The investigators found in clinical observation that the eyeball biological data of the Chinese population may not be consistent with the foreign population.

③ This study is the first study of human eye biological parameters based on different regions of large-scale populations in China, which is of great significance for understanding the human eye structure in different regions of China.

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Conditions studied

  • Cataract

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Keywords

  • Corneal astigmatism
  • axial length (AL), anterior chamber depth (ACD)
  • partial coherence interferometry
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In context

Cataract

1,701 studies on the registry are indexed under Cataract; 230 are open to participants now.

This study's planned enrollment of 20,000 is above the median of 81 across 484 observational studies indexed under Cataract.

Browse Cataract studies →

Lead sponsor

Aier School of Ophthalmology, Central South University is the lead sponsor of 18 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
50 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

Select elderly cataract patients from different regions of China (at least one representative city in each of east, south, west, north, and central China) who were treated in Aier Eye Hospital.

Inclusion criteria

  • patients aged over 50 years

Exclusion criteria

Exclusion Criteria:

  • history of refractive surgery,
  • corneal diseases
  • ocular inflammation
  • trauma
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Study design

Observational model
Case-only
Time perspective
Other
Enrollment
20,000 participants (estimated)
Patient registry
No

Groups and cohorts

  • Multi-center data collection

    Without intervention

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What researchers measure

Primary outcomes

  1. axial length (AL)

    Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)

    Time frame: 1 hour

  2. anterior chamber depth (ACD)

    Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)

    Time frame: 1 hour

  3. keratometric power (K)

    Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)

    Time frame: 1 hour

  4. corneal astigmatism (CA)

    Measured using the partial coherence laser interferometry (IOLMaster, Carl Zeiss Meditec, Germany)

    Time frame: 1 hour

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Study locations

1 of 1 sites recruiting
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References and documents

Publications

  • Qian Z, Xie X, Yang J, Ye H, Wang Z, Chen J, Liu H, Liang J, Jiang L, Zheng C, Chen X. Detection of shallow anterior chamber depth from two-dimensional anterior segment photographs using deep learning. BMC Ophthalmol. 2021 Sep 22;21(1):341. doi: 10.1186/s12886-021-02104-0. PubMed 34551738 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 9, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04340635
Lead sponsor
Aier School of Ophthalmology, Central South University
Responsible party
Sponsor
First posted
Apr 9, 2020
Start date
Jan 1, 2018
Primary completion
Oct 1, 2020 (estimated)
Completion
Dec 31, 2020 (estimated)
Last update
Apr 9, 2020

Study contacts

xu chen
Contact
Francois.chenxu@gmail.com
13601762646
hui liu
Contact
1009254042@qq.com
18570638843

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Apr 2020. You cannot join it, but the record below documents what was studied.

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Discussion

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