An interventional study of Non-surgical periodontal treatment and Saliva samples in Pregnancy Gingivitis, sponsored by Tokat Gaziosmanpasa University. Completed. Open to female participants aged 24 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-03-23.
Sponsored by Tokat Gaziosmanpasa University · Not applicable, Interventional, and Prevention
There is a relationship between stress and pregnancy gingivitis. This relationship may be double-sided.
The aim of this clinical study was to determine the effect of non-surgical mechanical periodontal treatment on sex steroid and stress markers at pregnancy gingivitis. A total of 84 subjects; 22 pregnant women with gingivitis (group 1) and 25 pregnant women with periodontal healthy (pregnant group), group 2), 22 non-pregnant women with gingivitis (group 3) and 15 non-pregnant women with periodontal healthy (non-pregnant group), group 4) participated in this study. Clinically, plaque index, gingival index, and probing pocket depth were measured at baseline and after therapy.
590 studies on the registry are indexed under Gingivitis; 104 are open to participants now.
This study's enrollment of 84 is above the median of 64 across 478 interventional studies indexed under Gingivitis.
Browse Gingivitis studies →Tokat Gaziosmanpasa University is the lead sponsor of 164 studies on the registry; 38 are open to participants now.
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Exclusion Criteria:
GCF and saliva samples were taken from pregnant gingivitis patients before treatment and after 8 weeks. GCF and saliva samples were taken from pregnant periodontal healty individuals baseline and after 8 weeks. Intervention: Non-surgical periodontal treatment was performed for pregnant gingivitis patients. Gingival crevicular fluid (GCF) and saliva samples were taken.
Other: Non-surgical periodontal treatment · Other: Saliva samples · Other: GCF samples
GCF and saliva samples were taken from non-pregnant gingivitis patients before treatment and after 8 weeks. GCF and saliva samples were taken from periodontal healty individuals baseline and after 8 weeks. Intervention: Non-surgical periodontal treatment was performed for non-pregnant gingivitis patients. Gingival crevicular fluid (GCF) and saliva samples were taken.
Other: Non-surgical periodontal treatment · Other: Saliva samples · Other: GCF samples
Non-surgical periodontal treatment was performed for pregnant and non-pregnant gingivitis patients. Gingival crevicular fluid (GCF) and saliva samples were taken from all patients baseline and after 8 weeks.
Saliva samples were taken from patients for the evaluation of sex steroid and stress markers baseline and after 8 weeks.
GCF samples were taken from patients for the evaluation of stress markers baseline and after 8 weeks.
Dehydroepiandrosterone (DHEA)
The changes in DHEA levels within 8 weeks. Higher values represent a worse outcome. The decrease in DHEA levels is expected after periodontal treatment.
Time frame: Baseline and after 8 weeks
estrogen
The changes in estrogen levels within 8 weeks. Higher values represent a worse outcome. The decrease in estrogen levels is expected after periodontal treatment.
Time frame: Baseline and after 8 weeks
Gingival index
The changes in gingival index level after periodontal treatment. Gingival index was measured for determining the severity of disease and clinical outcome. Higher values represent a worse outcome. After periodontal treatment, a reduction in gingival index value is expected.
Time frame: Baseline and after 8 weeks
No study locations are listed for this record.
This study is completed, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
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Tokat Gaziosmanpasa University