An interventional study of Motivational MRI and Behavioral Intervention and Control MRI and Behavioral Intervention in Aging, sponsored by Northeastern University. Completed at 1 site in United States. Open to participants aged 60 Years to 95 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-29.
Sponsored by Northeastern University · Not applicable, Interventional, and Basic science
In this six-week behavioral intervention, sedentary older adults will receive daily health messaging via their smart phone to better understand their daily activities and emotions. Participants undergo structural and functional brain imaging before and after the intervention along with measures of their behavioral, emotional and thinking functions.
This project will obtain data on the effects of a six week intervention designed to increase subjects' motivation to increase their physical activity. Subjects will be randomized into two different conditions to examine the efficacy of self-affirmation + positive messaging versus a control group that receives negative messaging only on changes in physical activity.
We will also examine whether any differential physical activity or structured exercise engendered in the two groups is maintained at 3 months post-intervention.
Secondary outcome measures will include a battery of cognitive, psychosocial, and neuroimaging measures that are designed to explicate the mechanisms that underlie motivation effects for physical activity in sedentary older adults.
Northeastern University is the lead sponsor of 55 studies on the registry; 21 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Brain MRI and Motivational Behavioral Intervention
Behavioral: Motivational MRI and Behavioral Intervention
Brain MRI and Control Behavioral Intervention
Behavioral: Control MRI and Behavioral Intervention
Motivational messaging delivered during a functional brain MRI scan and with daily messaging
Control messaging delivered during a functional brain MRI scan and with daily messaging
Change in Sedentary Behavior (Average Hour/Day)
This metric quantifies the change in the average amount of time spent sedentary each day in hours, from the baseline period to the 6-week follow-up period. It is a marker of time spent inactive.
Time frame: Baseline; 6-week
Change in Moderate-to-Vigorous Physical Activity
This measure focuses on the change in average moderate-to-vigorous physical activity (MVPA) daily minutes after the intervention compared to the pre-intervention average MVPA baseline.
Time frame: Baseline; 6-week
| Milestone | Intervention | Active Control |
|---|---|---|
| Started | 21 | 19 |
| Completed | 21 | 17 |
| Not completed | 0 | 2 |
This metric quantifies the change in the average amount of time spent sedentary each day in hours, from the baseline period to the 6-week follow-up period. It is a marker of time spent inactive.
| Change in average daily hours | Intervention | Active Control |
|---|---|---|
| Change in Sedentary Behavior (Average Hour/Day) | -0.11 ± 1.62 | 0.05 ± 1.61 |
This measure focuses on the change in average moderate-to-vigorous physical activity (MVPA) daily minutes after the intervention compared to the pre-intervention average MVPA baseline.
| Change in minutes daily | Intervention | Active Control |
|---|---|---|
| Change in Moderate-to-Vigorous Physical Activity | -0.17 ± 1.09 | 0.14 ± 0.41 |
Collected over Duration of the study (6-week intervention and baseline visit). Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Intervention | 0/21 (0%) | 0/21 (0%) | 0/21 (0%) |
| Active Control | 0/19 (0%) | 0/19 (0%) | 0/19 (0%) |
| Age, Continuous(years) | Intervention | Active Control | Total |
|---|---|---|---|
| Mean | 70.0 ± 5.4 | 68.4 ± 5.0 | 68.7 ± 5.2 |
| Sex: Female, Male(Participants) | Intervention | Active Control | Total |
|---|---|---|---|
| Female | 15 | 18 | 33 |
| Male | 6 | 1 | 7 |
| Race/Ethnicity, Customized(Participants) | Intervention | Active Control | Total |
|---|---|---|---|
| Black/African American | 7 | 0 | 7 |
| White/Caucasian | 12 | 17 | 29 |
| Asian/Pacific Islander | 2 | 1 | 3 |
| Other | 0 | 1 | 1 |
| Region of Enrollment(participants) | Intervention | Active Control | Total |
|---|---|---|---|
| United States | 21 | 19 | 40 |
| education(years) | Intervention | Active Control | Total |
|---|---|---|---|
| Mean | 16.6 ± 3.6 | 16.0 ± 3.6 | 16.3 ± 3.5 |
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This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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Northeastern University