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CompletedNCT04288505TANGOUpdated Jul 30, 2025

Evaluation of a Virtual Reality Tool for Identifying the Cognitive Functions of the Right Hemisphere in Patients With Brain Damage -TANGO

An interventional study of VIRTUAL REALITY application in Virtual Reality and Brain Damage, sponsored by University Hospital, Angers. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-07-30.

Sponsored by University Hospital, Angers · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
41
Allocation
Not applicable
Ages
18 Years and older
Sex
All
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Study summary

Evaluate the diagnostic performance of a virtual reality application to detect the presence of cognitive impairment of the non-dominant hemisphere in patients with brain damage

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Conditions studied

  • Virtual Reality
  • Brain Damage

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In context

Brain Injuries

2,112 studies on the registry are indexed under Brain Injuries; 384 are open to participants now.

This study's enrollment of 41 is below the median of 48 across 1,331 interventional studies indexed under Brain Injuries.

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Lead sponsor

University Hospital, Angers is the lead sponsor of 464 studies on the registry; 116 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Indication for brain lesion located in the right hemisphere surgery
  • Major patient
  • Karnofsky ≥ 70

Exclusion criteria

Exclusion Criteria:

  • Person with aphasia
  • Person with visual problems
  • Person with a contraindication to MRI
  • Person unable to carry out the tests planned in the study
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Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
41 participants (actual)

Study arms

  • Experimental
    single arm

    Diagnostic Test: VIRTUAL REALITY application

Interventions

  • Diagnostic testVIRTUAL REALITY application

    application on virtual reality headset

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What researchers measure

Primary outcomes

  1. Performance of the virtual reality application compared to classic cognitive tests batery for the detection of cognitive deficit

    Time frame: from surgery to 3 months after surgery

Secondary outcomes

  1. Performance of the virtual reality application compared with conventional cognitive tests used to detect visual-spatial attention disorders

    Time frame: from surgery to 3 months after surgery

  2. Performance of the virtual reality application compared with conventional cognitive tests used to detect facial emotion recognition disorders

    Time frame: from surgery to 3 months after surgery

  3. Performance of the virtual reality application compared with conventional cognitive tests, used to detect spatial attention disorders or the presence of facial emotion recognition disorders depending respectively on the location or type of facial emotion

    Time frame: from surgery to 3 months after surgery

  4. Study the reproducibility of the virtual reality application for detecting the presence of cognitive function disorders

    Time frame: from surgery to 3 months after surgery

  5. Study the correlation between visuo-spatial and facial emotion recognition deficits and possible tractographic changes

    Time frame: from surgery to 3 months after surgery

  6. Study the association between the presence of cognitive function deficits and the presence of behavioral disorders or health-related quality of life

    Time frame: from surgery to 3 months after surgery

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Study locations

1 site
  • University hospital
    Angers, 49000, France
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04288505
Lead sponsor
University Hospital, Angers
Responsible party
Sponsor
First posted
Feb 28, 2020
Start date
May 15, 2020
Primary completion
Feb 4, 2025
Completion
May 5, 2025
Last update
Jul 30, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.

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