An observational study in Nosocomial Pneumonia, sponsored by Zealand University Hospital. Completed at 1 site in Denmark. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-04-22.
Sponsored by Zealand University Hospital · Observational
Nosocomial pneumonia in the Intensive Care Unit is often not properly diagnosed mainly due to ongoing antimicrobial therapy. The study investigates the feasibility of more advanced diagnostic technics.
ICU patients fulfilling the CDC criteria for nosocomial pneumonia and mechanically ventilated for no more than 24 hours are included in the study. The material for the diagnostic procedure is pulmonal secretion collected by 1. suctioning in the tracheal tube and 2. bronchioalveolar lavage. The diagnostic procedures are culturing, 16S and18S gene PCR and subsequent sequencing. The 3 diagnostic methods will be compared in order of proper diagnosis and the ability to determine a specific antimicrobial treatment.
2,044 studies on the registry are indexed under Pneumonia; 283 are open to participants now.
This study's enrollment of 22 is below the median of 203 across 688 observational studies indexed under Pneumonia.
Browse Pneumonia studies →Zealand University Hospital is the lead sponsor of 234 studies on the registry; 51 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Adult patients with nosocomial pneumonia and the need of mechanical ventilation not intubated for more than 24 hours.
Exclusion Criteria:
Diagnostic procedures on pulmonary secretion collected by tracheal suctioning and bronchoalveolar lavage.
Diagnostic Test: Microbiological diagnostics on pulmonary secretion
Culture, 16s, 18s, next generation sequencing
Ratio of patients where the advanced methods are superior to routine
Ratio of patients diagnosed by 16s, 18s or NGS to total number of patients compared to ratio of patients diagnosed by routine method (culture)
Time frame: 1 day
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
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Zealand University Hospital