An interventional study of transcranial direct current stimulation and transcranial pulsed current stimulation in Traumatic Brain Injury, sponsored by Medical University of South Carolina. Withdrawn. Open to participants aged 25 Years to 70 Years. Per ClinicalTrials.gov, last updated 2022-01-04.
Sponsored by Medical University of South Carolina · Not applicable, Interventional, and Treatment
Transcranial electrical stimulation (tES) is a non-invasive form of brain stimulation that has previously been to shown to have therapeutic potential in traumatic brain injury (TBI) patients. In this study, the study team will use a brain activity monitor (electroencephalogram, EEG) and a computer-based task to observe the effects of different forms of tES, like transcranial direct current stimulation (tDCS) and transcranial pulsed current stimulation (tPCS), on impulse control and sustained attention in people with TBI. Additionally, the study team will measure how much tDCS and tPCS affect the brain activity of a specific area of the brain associated with impulse control and attention. Problems with response inhibition have been shown to make rehabilitation more difficult for people with TBI. It also reduces social functioning and can also negatively affect job performance, which ultimately lead to a decreased quality of life. A better understanding of the effects of tES in TBI patients could be informative in finding out what its therapeutic potential is for this population.
2,113 studies on the registry are indexed under Brain Injuries; 385 are open to participants now.
Browse Brain Injuries studies →Medical University of South Carolina is the lead sponsor of 852 studies on the registry; 165 are open to participants now.
Of its 128 completed or terminated interventional studies of FDA-regulated products, 101 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Device: transcranial direct current stimulation
Device: transcranial pulsed current stimulation
Device: Sham-no stimulation
Subjects in this arm will receive one session of tDCS for 20 minutes at 2.0 milliamps.
Subjects in this arm will receive one session of tPCS for 20 minutes at 2.0 milliamps.
Subjects in this arm will receive one session of sham for 20 minutes.
Average Reaction Time During Stop Signal Task
The Stop Signal Task (SST) is an assessment which requires participants to respond to various stimuli with a specific action and to not respond when a "stop" stimulus is presented.
Time frame: Throughout study (1 hour)
EEG power in all frequency bands
They will be fitted with a standard EEG cap consisting of 32 EEG electrodes placed in the 10/20 international system format, a standardized system for EEG electrode placement. Frequency bands will be measured.
Time frame: Baseline and immediately post Stimulation
No study locations are listed for this record.
Plan to share: Yes — Individual participant data that underlie the results reported in this article, after deidentification may be shared as well as the study protocol, statistical analysis plan, and analytic code.
Supporting information: Study protocol, Sap, Analytic code
No publications or documents are linked to this record.
This study is withdrawn, as verified in Dec 2021. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Medical University of South Carolina