An interventional study of PrEP campaign messages developed via open contest and PrEP campaign messages developed via social marketing approach in HIV/AIDS, sponsored by Johns Hopkins Bloomberg School of Public Health. Completed at 1 site in United States. Open to male participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-10-22.
Sponsored by Johns Hopkins Bloomberg School of Public Health · Not applicable, Interventional, and Prevention
The aim of this study is to examine the utility of neuroimaging technique to evaluate pre-exposure prophylaxis (PrEP) promotion messages for men who have sex with men (MSM) at risk of HIV in Baltimore.
This study will examine the utility of neuroimaging technique to evaluate PrEP promotion messages for MSM at risk of HIV in Baltimore. The investigators hypothesize that participants viewing top messages developed via open contests will show higher brain activation in the Medial Prefrontal Cortex (MPFC) regions than those viewing messages developed by a social marketing approach. The investigators further hypothesize brain activation in the MPFC regions is significantly more correlated with PrEP behavioral intention, initiation, and action than self-reported message effectiveness.
2,099 studies on the registry are indexed under Acquired Immunodeficiency Syndrome; 273 are open to participants now.
This study's enrollment of 23 is below the median of 104 across 1,590 interventional studies indexed under Acquired Immunodeficiency Syndrome.
Browse Acquired Immunodeficiency Syndrome studies →Johns Hopkins Bloomberg School of Public Health is the lead sponsor of 369 studies on the registry; 41 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 3 (60%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
- Participated in open contest
Participants will view the top PrEP-promotion messages developed via an open contest.
Behavioral: PrEP campaign messages developed via open contest
Participants will view the PrEP-promotion messages developed via social marketing.
Behavioral: PrEP campaign messages developed via social marketing approach
PrEP campaign messages will be developed via an open contest in Baltimore.
PrEP campaign messages developed with a traditional social marketing approach.
Change of Willingness to Take PrEP
Questions on willingness to take PrEP. Participants will be asked, "Suppose that PrEP is at least 90% effective in preventing HIV when taken daily. How likely would you be to take PrEP if it were available for free?" with responses ranging from "Extremely unlikely-1," "Somewhat unlikely-2," "Somewhat likely-3," "Extremely likely-4." The mean of the changes between baseline and after participants reviewed the messages was calculated.
Time frame: baseline, 30 days post baseline
| Milestone | Open Contest Messages | Social Marketing Messages |
|---|---|---|
| Started | 14 | 9 |
| Completed | 14 | 9 |
| Not completed | 0 | 0 |
Questions on willingness to take PrEP. Participants will be asked, "Suppose that PrEP is at least 90% effective in preventing HIV when taken daily. How likely would you be to take PrEP if it were available for free?" with responses ranging from "Extremely unlikely-1," "Somewhat unlikely-2," "Somewhat likely-3," "Extremely likely-4." The mean of the changes between baseline and after participants reviewed the messages was calculated.
| units on a scale | Open Contest Messages | Social Marketing Messages |
|---|---|---|
| Change of Willingness to Take PrEP | 0 ± 0 | 0.5 ± 0.71 |
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Open Contest Messages | — | — | — |
| Social Marketing Messages | — | — | — |
| Age, Categorical(Participants) | Open Contest Messages | Social Marketing Messages | Total |
|---|---|---|---|
| <=18 years | 0 | 0 | 0 |
| Between 18 and 65 years | 13 | 9 | 22 |
| >=65 years | 1 | 0 | 1 |
| Age, Continuous(years) | Open Contest Messages | Social Marketing Messages | Total |
|---|---|---|---|
| Mean | 34 (23 to 65) | 32 (24 to 56) | 33 (23 to 65) |
| Sex: Female, Male(Participants) | Open Contest Messages | Social Marketing Messages | Total |
|---|---|---|---|
| Female | 0 | 0 | 0 |
| Male | 14 | 9 | 23 |
| Race (NIH/OMB)(Participants) | Open Contest Messages | Social Marketing Messages | Total |
|---|---|---|---|
| American Indian or Alaska Native | 0 | 0 | 0 |
| Asian | 0 | 0 | 0 |
| Native Hawaiian or Other Pacific Islander | 0 | 0 | 0 |
| Black or African American | 13 | 8 | 21 |
| White | 1 | 1 | 2 |
| More than one race | 0 | 0 | 0 |
| Unknown or Not Reported | 0 | 0 | 0 |
| Region of Enrollment(Participants) | Open Contest Messages | Social Marketing Messages | Total |
|---|---|---|---|
| United States | 14 | 9 | 23 |
| Interntion to use PrEP(units on a scale) | Open Contest Messages | Social Marketing Messages | Total |
|---|---|---|---|
| Mean | 3 ± 1.20 | 3.6 ± 0.55 | 3.18 ± 1.07 |
Documents are hosted by the registry — open the source record to download them.
This study is completed, as verified in Sep 2024. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Acquired Immunodeficiency Syndrome →
Johns Hopkins Bloomberg School of Public Health →