CClinicalTrials.gg
CompletedNCT04085133Updated Feb 17, 2023

Prevalence and Burden of Bronchiectasis in Tuberculous Patients

An observational study in Pulmonary Tuberculoses, sponsored by Assiut University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2023-02-17.

Sponsored by Assiut University · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
50
Ages
18 Years to 50 Years
Sex
All
01

Study summary

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree

Read the detailed description

Bronchiectasis was described in the early 19th century by Laennec. Bronchiectasis is a chronic condition characterized by permanent and irreversible dilatation of the bronchial airways and impairment of mucociliary transport mechanism due to repeated infection and inflammation leading to colonization of organism and pooling of the mucus in the bronchial tree.

The prevalence of bronchiectasis is age-related and occurs in every age group and in the pre-antibiotic era . it most often began in childhood. Recent evidence shows that bronchiectasis disproportionately affects women and older individuals and will be contributing to increase in healthcare burden.[3] International data show an increase in the prevalence of bronchiectasis over recent years.

02

Conditions studied

03

In context

Tuberculosis

1,417 studies on the registry are indexed under Tuberculosis; 208 are open to participants now.

This study's enrollment of 50 is below the median of 250 across 421 observational studies indexed under Tuberculosis.

Browse Tuberculosis studies →

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Sampling method
Probability sample

Study population

Any tuberculosis patients admited to assuit university hospital and assuit chest hospital

Inclusion criteria

  • 1-patients were diagnosed to have tuberculosis by sputum culture and gene x pert.

    2-patients were diagnosed to have bronchiectasis after lab and radiological examination as well as clinical score.

    3- patients diagnosed as bronchiectasis after history of tuberculosis or anti Tuberculosis treatment with positive or negative tuberculous culture in the time of research.

Exclusion criteria

Exclusion Criteria:

  • 1-patients presented with other Pulmonary diseases. 2-Chronic liver and renal disease . 3- Lung cancer and tumors. 4- patients were previously diagnosed as bronchiectasis .
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
50 participants (actual)
Target follow-up
2 Weeks
Patient registry
Yes
Biospecimen retention
Samples with dna

Interventions

  • Diagnostic testGene Xpert Chest x ray and MSCT chest

    Sputum sample for T.B will be done using gene expert device and chest xray and high resolution ct to evaluate bronchectasis

06

What researchers measure

Primary outcomes

  1. To study prevalence of bronchiectasis in TB patients by case per year.

    How many patients of TB will be diagnosed as abronchiectasis

    Time frame: One year

Secondary outcomes

  1. To evaluate the burden of bronchiectasis in TB patients

    by frequency of need for hospital admission per year, need for outpatient clinical visits per month and frequency of need for antimicrobial therapy other than anti-tuberculous treatment per month

    Time frame: one year

07

Study locations

1 site
  • Assiut unviresty
    Assiut, 71511, Egypt
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 17, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT04085133
Lead sponsor
Assiut University
Responsible party
Ahmad Shaddad (DR.Ahmad Shaddad, Assiut University) — Principal investigator
First posted
Sep 11, 2019
Start date
Sep 26, 2019
Primary completion
Jan 1, 2020
Completion
Apr 1, 2020
Last update
Feb 17, 2023

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion