CClinicalTrials.gg
Status unknownNCT04068324Updated Mar 19, 2020

Postoperative Recovery Quality According to Preoperative Fasting Time in Pediatric Patients Undergoing Nuss Operation

An interventional study of New Care No Nil Per Os in Pectus Excavatum, sponsored by Jung Min Koo. Status unknown at 1 site in Korea, Republic of. Open to participants aged 3 Years to 6 Years. Per ClinicalTrials.gov, last updated 2020-03-19.

Sponsored by Jung Min Koo · Not applicable, Interventional, and Supportive care

The sponsor has not verified this record recently (last verified Mar 2020), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
3 Years to 6 Years
Sex
All
01

Study summary

Preoperative fasting is intended to lower the amount of gastric contents in order to decrease the incidence of aspiration associated with endotracheal intubation. However, recent studies show that longer fasting time does not reduce aspiration associated complications. Especially in pediatric patients, long fasting time increases patients' unpleasantness and therefore increases postoperative recovery quality. It also induces hypoglycemia. In many studies, ingesting clear liquids 2 hours up to general anesthesia decreases gastric contents and therefore the incidence of aspiration pneumonia, postoperative nausea and vomiting. Therefore anesthesiologist associations in the US and Europe recommend to drink small amount of clear liquid (water) up to 2 hours before the surgery.

Nuss bar operation, or repair surgery of pectus excavatum is mostly done in pediatric patients. The procedure itself is very painful, requiring paramount amount of analgesics. Use of opioid analgesics increases postoperative nausea and vomiting.

In this study, our aim is to evaluate preoperative fasting time and how preoperative supplement of clear liquid affects the quality of recovery postoperatively.

02

Conditions studied

  • Pectus Excavatum

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03

Who can participate

Ages eligible
3 Years to 6 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Pediatric patients from age 3 to 6
  2. Undergoing repair surgery for pectus excavatum
  3. American Society of Anesthesiologists class I to III

Exclusion criteria

Exclusion Criteria:

  1. Any diseases or past surgical procedures involving gastrointestinal tract
  2. Past history of psychiatric diseases
  3. On chronic analgesic medication
  4. Patients or Patients' caregivers do not agree to attend the study
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Factorial assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
90 participants (estimated)

Study arms

  • No intervention
    8 hours fasting group

    Routine preoperative fasting group undergoes 8 hours of fasting before the operation.

  • Experimental
    Clear liquid group

    30 pediatric patients drink 3ml/kg 1 hour before the surgery. Although "clear liquid" suggests any drinks that do not contain any solid ingredients, but in this study we define "clear liquid" as water.

    Dietary Supplement: New Care No Nil Per Os

  • Experimental
    Carbohydrate containing liquid group

    Other 30 pediatric patients drink 3ml/kg of carbohydrate containing fluid 1 hour before the surgery. The product name we have is "NoNPO" from NewCare (South Korean company). This fluid does not contain any solid ingredients, so consuming the fluid does not exceed Nil per Os time needed before the surgery.

    Dietary Supplement: New Care No Nil Per Os

Interventions

  • Dietary supplementNew Care No Nil Per Os

    The product name "NoNPO" is from South Korean company "Well life." It contains carbohydrate and is frequently used in preoperative fasting patients in order to alleviate patients' discomfort resulting from empty stomach and thirst. It is also known to decrease insulin resistant.

05

What researchers measure

Primary outcomes

  1. Modified-Yale Preoperative Anxiety Scale

    MyPas scale measures 4 categories: Activity, Vocalizations, Emotional Expressivity and State of Apprent Arousal. Each category has 1 to 4 scales for activity, emotional expresivity and state of apprent arousal, and 1 to 6 for vocalizations, that each describes the child's anxiety status. The observer collects total score ranging from 4 to 18.

    Time frame: Preoperatively at the surgery waiting room

  2. Emergence delirium

    "Watcha scale" measures child's postoperative delirium at the recovery center. The total score ranges from 0 to 4. 0 is when the child is asleep, 1 is calm and sedated, 2 is when the child is crying but consolable, 3 is when the child is crying and unconsolable, and 4 is when the child is uncontrollable.

    Time frame: 5 Minutes postoperatively at postoperative discharge unit

  3. Emergence delirium

    "Watcha scale" measures child's postoperative delirium at the recovery center. The total score ranges from 0 to 4. 0 is when the child is asleep, 1 is calm and sedated, 2 is when the child is crying but consolable, 3 is when the child is crying and unconsolable, and 4 is when the child is uncontrollable.

    Time frame: 10 Minutes postoperatively at postoperative discharge unit

  4. Emergence delirium

    "Watcha scale" measures child's postoperative delirium at the recovery center. The total score ranges from 0 to 4. 0 is when the child is asleep, 1 is calm and sedated, 2 is when the child is crying but consolable, 3 is when the child is crying and unconsolable, and 4 is when the child is uncontrollable.

    Time frame: 15 Minutes postoperatively at postoperative discharge unit

  5. Emergence delirium

    "Watcha scale" measures child's postoperative delirium at the recovery center. The total score ranges from 0 to 4. 0 is when the child is asleep, 1 is calm and sedated, 2 is when the child is crying but consolable, 3 is when the child is crying and unconsolable, and 4 is when the child is uncontrollable.

    Time frame: 30 Minutes postoperatively at postoperative discharge unit

  6. Emergence delirium

    "Watcha scale" measures child's postoperative delirium at the recovery center. The total score ranges from 0 to 4. 0 is when the child is asleep, 1 is calm and sedated, 2 is when the child is crying but consolable, 3 is when the child is crying and unconsolable, and 4 is when the child is uncontrollable.

    Time frame: 45 Minutes postoperatively at postoperative discharge unit

  7. Emergence delirium

    "Watcha scale" measures child's postoperative delirium at the recovery center. The total score ranges from 0 to 4. 0 is when the child is asleep, 1 is calm and sedated, 2 is when the child is crying but consolable, 3 is when the child is crying and unconsolable, and 4 is when the child is uncontrollable.

    Time frame: 60 Minutes postoperatively

  8. Pain Score

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: 5 minutes postoperatively at postoperative discharge unit

  9. Pain Score

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: 10 minutes postoperatively at postoperative discharge unit

  10. Pain Score

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: 15 minutes postoperatively at postoperative discharge unit

  11. Pain Score

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: 30 minutes postoperatively at postoperative discharge unit

Secondary outcomes

  1. Pain scores

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: Between 1~6 hours postoperatively

  2. Pain scores

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: Between 12~24 hours postoperatively

  3. Pain scores

    Face, Legs, Activity, Cry and Consolability score: This is a measurement for pediatric pain. The observer observes the child's face, legs, activity, cry and consolability. The score ranges from 0 to maximum of 8. 0 is when the child is calm without any pain, and 8 being the most painful expression of the child.

    Time frame: Between 24~48 hours postoperatively

  4. Other pro re nata analgesics used, amount and type

    Analgesics applied in the ward according to the child's pain scale or as requested by his or her parents

    Time frame: Between 1~6 hours postoperatively

  5. Other pro re nata analgesics used, amount and type

    Analgesics applied in the ward according to the child's pain scale or as requested by his or her parents

    Time frame: Between 12~24 hours postoperatively

  6. Other pro re nata analgesics used, amount and type

    Analgesics applied in the ward according to the child's pain scale or as requested by his or her parents

    Time frame: Between 24~48 hours postoperatively

  7. Any postoperative side effects

    Time frame: Between 1~6 hours postoperatively

  8. Any postoperative side effects

    Time frame: Between 12~24 hours postoperatively

  9. Any postoperative side effects

    Time frame: Between 24~48 hours postoperatively

06

Study locations

1 of 1 sites recruiting
  • Jung Min Koo
    Seoul, Korea, Republic of
    Recruiting
07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT04068324
Lead sponsor
Jung Min Koo
Responsible party
Jung Min Koo (Principal Investigator, Seoul St. Mary's Hospital) — Sponsor-investigator
First posted
Aug 28, 2019
Start date
Aug 30, 2019
Primary completion
Jan 28, 2021 (estimated)
Completion
Feb 28, 2021 (estimated)
Last update
Mar 19, 2020

Study contacts

Jung Min Koo, MD
Contact
miniyaa623@gmail.com
+821051685538
Jung Min Koo, MD
principal investigator · Seoul St. Mary's Hospital, South Korea

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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