An observational study in Glaucoma, sponsored by Portsmouth Hospitals NHS Trust. Completed at 1 site in United Kingdom. Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2023-04-07.
Sponsored by Portsmouth Hospitals NHS Trust · Observational
The study is a prospective observational study where participants will be recruited from the Ophthalmology department (Outpatient department, Eye Casualty). Only one research visit will be required. Participants will be asked to fill in a set of questionnaires (Visual Functioning Questionnaire-15(61), Low Luminance Questionnaire(62)) assessing their quality of life and vision and their full medical history will be collected. Then they will have their contrast sensitivity tested under various light conditions. If a recent visual field test is not available, that might be performed as part of the study.
The purpose of our, real world study is to explore contrast sensitivity differences after changes in ambient light setting in patients with glaucoma compared with controls (patients with ocular hypertension). Participants will be asked to read a Pelli- Robson chart under photopic (bright light conditions) and mesopic (intermediate light conditions); followed by scotopic conditions (dim light conditions). This chart is a fast, easy, and effective way to measure spatial contrast sensitivity with reliable and reproducible results(60). This study will therefore help clinicians gain more insight into glaucoma related disability and provide a possible additional tool to visual field testing in patients with advanced glaucoma where VF testing may be hampered by floor effects.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 115 is above the median of 103 across 454 observational studies indexed under Glaucoma.
Browse Glaucoma studies →Portsmouth Hospitals NHS Trust is the lead sponsor of 74 studies on the registry; 15 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with a diagnosis of glaucoma (including primary open angle glaucoma, pigment dispersion syndrome, pseudoexfoliation, normal tension glaucoma, chronic angle closure glaucoma, narrow angle glaucoma) or ocular hypertension aged ≥40 years old.
Male or Female, aged 40 years or above.
Exclusion Criteria:
Neovascular, uveitic, acute angle closure glaucoma
vision-related quality of life in patients with glaucoma
assessed using the the visual functioning questionnaire - 25 questionnaire
Time frame: 1 day study visit
Visual function
assessed using the low luminance questionnaire
Time frame: through study completion, an average of 1 year
To correlate visual impairment with contrast sensitivity results
measured with Quality of Life questionnaires (Visual Functioning Questionnaire-25, Low Luminance Questionnaire)
Time frame: through study completion, an average of 1 year
Contrast Sensitivitiy
Participants' contrast sensitivity will be tested under photopic (bright light conditions), mesopic (intermediate light conditions) and/or scotopic conditions (dim light conditions).
Time frame: through study completion, an average of 1 year
This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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Portsmouth Hospitals NHS Trust