An interventional study of Non-surgical periodontal treatment in Periodontitis, sponsored by T.C. ORDU ÜNİVERSİTESİ. Completed at 1 site in Turkey. Open to participants aged 25 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-08-12.
Sponsored by T.C. ORDU ÜNİVERSİTESİ · Not applicable, Interventional, and Diagnostic
The aim of this study was to evaluate the levels of lipoxin A4 (LXA4), prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) in gingival crevicular fluid (GCF) and saliva in individuals with periodontal healthy and chronic periodontitis. In addition, the investigators evaluated the levels of these mediators after non-surgical periodontal treatment in patients with chronic periodontitis. A total of 20 subjects, 10 patients with chronic periodontitis (CP) and 10 periodontally healthy individuals were included in the study. Clinical parameters including plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment levels (CAL) were recorded. GCF and saliva samples were obtained at the beginning of the study from all individuals. GCF and saliva samples were re-collected from patients with CP at 1 month after non surgical periodontal therapy.
1,635 studies on the registry are indexed under Periodontitis; 327 are open to participants now.
This study's enrollment of 20 is below the median of 45 across 1,191 interventional studies indexed under Periodontitis.
Browse Periodontitis studies →T.C. ORDU ÜNİVERSİTESİ is the lead sponsor of 87 studies on the registry; 12 are open to participants now.
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Exclusion Criteria:
Periodontally healthy group
Patients with chronic periodontitis
Procedure: Non-surgical periodontal treatment
Mechanical non-surgical treatment were performed
Lipoxin A4 levels
change of gingival crevicular fluid and salivary Lipoxin A4 levels from baseline at 1st month
Time frame: 1st month
Prostaglandin E2 levels
change of gingival crevicular fluid and salivary Prostaglandin E2 levels from baseline at 1st month
Time frame: 1st month
Leukotriene B4
change of gingival crevicular fluid and salivary Leukotriene B4 levels from baseline at 1st month
Time frame: 1st month
Plan to share: No
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This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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T.C. ORDU ÜNİVERSİTESİ