An observational study in Acute Myocardial Infarction, sponsored by Assistance Publique - Hôpitaux de Paris. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-06-25.
Sponsored by Assistance Publique - Hôpitaux de Paris · Observational
Over the last two decades, considerable progress has been made in the management of Acute Myocardial Infarction (AMI), both in the acute phase and in monitoring beyond the hospital phase. Nevertheless, the evolution of care practices and their impact on the mid- and long-term prognosis of patients admitted to the intensive care unit for acute myocardial infarction remain relatively little studied exhaustively.
The aim of this study is to assess the profile of AMI patients, their management and follow-up in order to evaluate the relationship between these factors and outcomes.
The FRENCHIE registry is a French multicenter prospective observational study. All the eligible consecutive patients admitted within 48 hours after symptom onset in a cardiac ICU for an acute myocardial infarction.
This hospital registry will be linked to the national databases, in order to collect follow-up clinical outcomes and health care consumption.
Assistance Publique - Hôpitaux de Paris is the lead sponsor of 3,505 studies on the registry; 1,006 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Consecutive eligible (cf eligibility criteria) patients admitted in one of the Intensive Coronary Units participating to the study.
Exclusion Criteria:
As it is an observational study, no intervention is planned. However, nested clinical interventional trials are planned for which a specific registration will be done
In-hospital mortality
In-hospital mortality
Time frame: Through the end of initial hospitalization, an average of 5 days
In-hospital outcomes
To measure the in-hospital major cardiovascular events : recurrence of AMI, myocardial revascularization, stroke
Time frame: Through the end of initial hospitalization, an average of 5 days
Lipopretein 1 evolution
To evaluate plasma concentrations of Lpa and its dynamic pattern during hospital index and 3-9 months following hospitalization.
Time frame: 9 months after the end of initial hospitalization
Cardiovascular outcomes during follow-up
All cause death and Cardiovascular events including non fatal Myocardial Infarction, non fatal stroke, revascularization, hospitalization for other cardiovascular causes including Bleeding leading to hospitalization
Time frame: Up to 20 years
Non cardiovascular outcomes during follow-up
All cause death and Non-cardiovascular events leading to to hospitalizations
Time frame: Up to 20 years
Relationship between patients profile and mortality and cardiovascular morbidity outcomes according to management
All cause death and cardiovascular events including non fatal MI, non fatal stroke, revascularization, hospitalization for other cardiovascular causes including Bleeding leading to hospitalization according to patient's management
Time frame: Up to 20 years
Relationship between patients profile and mortality and non-cardiovascular morbidity outcomes according to management
All cause death and Non-cardiovascular events leading to to hospitalizations according to patient's management
Time frame: Up to 20 years
Oral comorbidities
Prevalence of oral pathology and its relationship with early, mid, and long-term prognosis and outcomes
Time frame: Up to 20 years
Sleep disordered breathing comorbidities
To assess the prevalence of sleep disordered breathing comorbidities and the relationship with early, mid, and long-term prognosis and outcomes
Time frame: Up to 20 years
Evaluate the path of care combined with patient care practices following an acute myocardial infarction
Evaluate the path of care and patient care practices following an acute myocardial infarction : Reimbursed or prescribed treatments, combined with number of visits, biological and tests performed
Time frame: Up to 20 years
Evaluate the relevance of European Society of Cardiology (ESC), American Heart Association/American College of Cardiology (AHA / ACC) guidelines regarding management of AMI patients
Evaluate the relevance of ESC, AHA/ACC guidelines regarding management of AMI patients
Time frame: Up to 20 years
Cost-utility: incremental (or decremental) cost-utility ratio during follow-up
Medical care costs for the index hospitalization and during follow-up period are assessed using a combination of resource-based and event-based methods. In-hospital resource utilization are based on diagnosis and procedural codes and length of stay.
Time frame: Up to 20 years
Plan to share: Undecided
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Assistance Publique - Hôpitaux de Paris