CClinicalTrials.gg
WithdrawnNCT04035928Updated Jun 24, 2024

Digital Design for Maxillofacial Prosthetics

An interventional study of 3D digital scanning for maxillofacial prosthetics in Prosthetic Treatment, Craniofacial Abnormalities and Maxillofacial Abnormalities, sponsored by University of Michigan. Withdrawn at 1 site in United States. Open to participants aged 6 Years and older. Per ClinicalTrials.gov, last updated 2024-06-24.

Sponsored by University of Michigan · Not applicable, Interventional, and Other

Why this study was withdrawn
Recruitment never initiated, change of staff
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Not applicable
Ages
6 Years and older
Sex
All
01

Study summary

This study will use a 3D scanner to print a 3D model or mold for each patient's prosthesis. The goal of this study to provide patients with a new, faster method of imaging and creating prostheses that preserves the quality of the current method while reducing time spent by both the patient and providers. Patients that are eligible will have a non-invasive 3D scanner (Artec Space Spider) to image the indicated areas of their head and face to help create their new prosthesis. Patients will come in for visits as needed to fit and adjust their prosthetic. Additionally, patients will be asked to complete questionnaires and have follow-up visits at certain time -points pre and post prosthetic completion.

02

Conditions studied

  • Prosthetic Treatment
  • Craniofacial Abnormalities
  • Maxillofacial Abnormalities

Keywords

  • prosthetic treatment
  • rhinectomy
03

Who can participate

Ages eligible
6 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Maxillofacial anatomic defect or anomaly that limits function or cosmesis (including facial and/or intraoral)
  • Stable defect (no clinically active tumor or plans for major reconstructive surgery)
  • The patient (or family) have elected to pursue a prosthetic reconstruction of a craniofacial anomaly
  • The patient is amenable to 3D surface scanning rather than facial molding

Exclusion criteria

Exclusion Criteria:

  • Known allergy to silicone
  • Poor candidate for prosthetic reconstruction
  • Developmental concerns regarding aspiration risk
04

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    3D digital scanning for maxillofacial prosthetics

    Device: 3D digital scanning for maxillofacial prosthetics

Interventions

  • Device3D digital scanning for maxillofacial prosthetics

    The non-invasive Artec Space Spider 3D scanner will be used to image the indicated areas of the patients head and face. In the case of an intraoral defect, the noninvasive TRIOS intraoral 3D scanner will be used. The study may also use nasometry or nasal endoscopy to measure the amount of airflow through the patient's fistula to help guide the design. The software that will be used will create a 3D image of the prosthesis during the patient's clinic appointment. Once a model of the prosthesis is fully designed and manufactured, the patient will return to clinic for a second appointment which may involve fitting and coloring. A subsequent appointment will involve delivery of a successfully fitted and colored prosthesis that the patient will take home.

05

What researchers measure

Primary outcomes

  1. Number or weeks to create the final prosthesis

    Time frame: up to 6 months

  2. Time the participants spend in the clinic

    This includes time spent with participant to design the prosthetic

    Time frame: up to 6 months

  3. Number of hours spent to create the prosthetic

    The number of hours will be calculated by using the design software, scanners, printing, and modifying the mold and prosthesis.

    Time frame: up to 6 months

Secondary outcomes

  1. Satisfaction measured by modified Toronto Outcome Measure of Craniofacial Prosthetics (TOMCP) for intraoral prosthesis.

    Survey questions are all created using a 7-point Likert scale for assessment. Questions 10-17 from the survey will be used to measure the patients prosthesis level of satisfaction (the higher the score the more satisfied). These will be completed pre-prosthesis and at 1 month and 6 months post prosthesis for patients with intraoral prosthesis.

    Time frame: up to 6 months after the prosthetic is completed and being used

  2. Satisfaction measured by modified Toronto Outcome Measure of Craniofacial Prosthetics (TOMCP) for extraoral prosthesis.

    Survey questions are all created using a 7-point Likert scale for assessment. Questions 8-19 from the survey will be used to measure the patients level of satisfaction (the higher the score the more satisfied). These will be completed pre-prosthesis and at 1 month and 6 months post prosthesis for patients with extraoral prosthesis.

    Time frame: up to 6 months after the prosthetic is completed and being used

  3. Quality of life measures by modified Toronto Outcome Measure of Craniofacial Prosthetics (TOMCP) for intraoral prosthesis.

    Survey questions are all created using a 7-point Likert scale for assessment. Questions 1-9 from the survey will be used to measure the patients level of quality of life (the higher score indicates better quality). These will be completed pre-prosthesis and at 1 month and 6 months post prosthesis for patients with intraoral prosthesis.

    Time frame: up to 6 months after the prosthetic is completed and being used

  4. Quality of life measures by modified Toronto Outcome Measure of Craniofacial Prosthetics (TOMCP) for extraoral prosthesis.

    Survey questions are all created using a 7-point Likert scale for assessment. Questions 1-7 from the survey will be used to measure the patients quality of life (the higher score indicates be better quality). These will be completed pre-prosthesis and at 1 month and 6 months post prosthesis for patients with extraoral prosthesis.

    Time frame: up to 6 months after the prosthetic is completed and being used

  5. Number of adverse events related to the prosthetic

    This study will collect and report adverse events (serious and non-serious) at least possibly related to the prosthetic.

    Time frame: up to 6 months after the prosthetic is completed and being used

06

Study locations

1 site
  • University of Michigan
    Ann Arbor, Michigan 48170, United States
07

Registry details

Key details

Study ID
NCT04035928
Lead sponsor
University of Michigan
Responsible party
David Zopf (Assistant Professor of Otorhinolaryngology, University of Michigan) — Principal investigator
First posted
Jul 29, 2019
Start date
Oct 14, 2019
Primary completion
Jul 2023 (estimated)
Completion
Jul 2023 (estimated)
Last update
Jun 24, 2024

Study contacts

David Zopf, MD
principal investigator · University of Michigan

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Jun 2024. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion