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CompletedNCT04022486BRONCHIOLITISUpdated Jul 17, 2019

Seizures in Infants Hospitalized in Pediatric Intensive Care Unit for Bronchiolitis

An observational study in Bronchiolitis, Seizures and Hyponatremia, sponsored by Hospices Civils de Lyon. Completed at 1 site in France. Open to participants aged Up to 90 Days. Per ClinicalTrials.gov, last updated 2019-07-17.

Sponsored by Hospices Civils de Lyon · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
805
Ages
Up to 90 Days
Sex
All
01

Study summary

Bronchiolitis is the leading cause of pediatric intensive care unit admission in infants. Seizures during bronchiolitis may be a neurological complication of respiratory viruses but also of the treatments. The investigating team's hypothesis is that the incidence of seizures is not so so uncommon in infants hospitalized in the pediatric intensive care unit for severe bronchiolitis.

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Conditions studied

  • Bronchiolitis
  • Seizures
  • Hyponatremia

Keywords

  • Infant
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In context

Bronchiolitis

360 studies on the registry are indexed under Bronchiolitis; 43 are open to participants now.

This study's enrollment of 805 is above the median of 196 across 92 observational studies indexed under Bronchiolitis.

Browse Bronchiolitis studies →

Lead sponsor

Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Up to 90 Days
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All children hospitalized in the pediatric intensive care unit

Inclusion criteria

  • age \< 90 days
  • hospitalization from January 1st, 2010 to April 30th, 2018 in the Pediatric Intensive Care Unit (PICU) of pediatric hospital in Lyon
  • with bronchiolitis (clinical diagnosis according to American Academy of Pediatrics)

Exclusion criteria

Exclusion Criteria:

  • neurological history that may explain the occurrence of seizures
  • significant congenital heart disease
05

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
805 participants (actual)
Patient registry
No

Groups and cohorts

  • Children admitted in the PICU for severe bronchiolitis

    Children admitted in the Pediatric Intensive Care Unit (PICU) for severe bronchiolitis between January 1st, 2010 and April 30th, 2018

    Other: Incidence, management and risk factors of seizure

Interventions

  • OtherIncidence, management and risk factors of seizure

    Incidence of seizure, management (treatment, paraclinical examinations) and risk factors of seizure in children admitted for severe bronchiolitis

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What researchers measure

Primary outcomes

  1. : Incidence of seizure during bronchiolitis (before or during hospitalization in the pediatric intensive care unit)

    Clinical or infra-clinical (diagnosed on Electroencephalography, EEG) seizure, simple or status epilepticus

    Time frame: Day 1

07

Study locations

1 site
  • Hôpital Femme Mère Enfant
    Bron, 69677, France
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 17, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT04022486
Lead sponsor
Hospices Civils de Lyon
Responsible party
Sponsor
First posted
Jul 17, 2019
Start date
Apr 1, 2018
Primary completion
Aug 1, 2018
Completion
May 1, 2019
Last update
Jul 17, 2019

Study contacts

Florent BAUDIN, MD
principal investigator · Hospices Civils de Lyon

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.

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