An interventional study of Bifidobacterium triple live capsule and Placebos in Necrosis of Femoral Head, Knee Osteoarthritis and Fracture of Neck of Femur, sponsored by RenJi Hospital. Status unknown at 3 sites in China. Open to participants aged 65 Years to 80 Years. Per ClinicalTrials.gov, last updated 2022-05-02.
Sponsored by RenJi Hospital · Not applicable, Interventional, and Prevention
The aim of this study was to evaluate whether perioperative probiotics can reduce the incidence of postoperative cognitive dysfunction and postoperative delirium.
477 studies on the registry are indexed under Intervertebral Disc Displacement; 103 are open to participants now.
This study's planned enrollment of 220 is above the median of 63 across 344 interventional studies indexed under Intervertebral Disc Displacement.
Browse Intervertebral Disc Displacement studies →RenJi Hospital is the lead sponsor of 535 studies on the registry; 244 are open to participants now.
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The probiotic group was treated with Bifidobacterium tripleis,one day before surgery to the sixth day after surgerythe drug is taken orally, 4 capsules at a time, 2 times a day.
Drug: Bifidobacterium triple live capsule
The control group was given the same package of placebo,one day before surgery to the sixth day after surgery. The drug is taken orally, 4 capsules at a time, 2 times a day.
Drug: Placebos
Bifidobacterium triple live capsules, indications for acute and chronic diarrhea and constipation caused by intestinal flora imbalance, can also be used for the treatment of mild to moderate acute diarrhea, chronic diarrhea and indigestion, bloating, and adjuvant treatment of intestinal flora Endotoxemia caused by disorders.
Also known as: Peifei Kang Capsule
Placebos were administrated as same as the bifidobacterium live capsule
Also known as: Placebo
Incidence of POCD 7days after surgery
Time frame: The seventh day after surgery
Incidence of POCD 1 month after operation
Time frame: One month after surgery
Incidence of POD 7 days after surgery
Use the CAM scale to assess whether a patient has postoperative delirium
Time frame: One day after surgery to the seventh day after surgery
This study is status unknown, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.
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Intervertebral Disc Displacement→
RenJi Hospital