An interventional study of Behavorial; memory exercise and Placebo; memory exercise in Spinal Cord Injuries, sponsored by Kessler Foundation. Completed at 1 site in United States. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2023-01-18.
Sponsored by Kessler Foundation · Not applicable, Interventional, and Treatment
The purpose of this research study is to investigate the effectiveness of a memory retraining program and a processing speed program in a spinal cord injured (SCI) population. The study is designed to research how well different types of techniques can help people with SCI improve in areas where they might have difficulties such as memory or processing speed, (time it takes to process information provided).
The objectives of the currently proposed randomized clinical trial are to (1) apply a treatment protocol for Processing Speed and Learning and memory impairments, well-validated in other neurological populations, to individuals with SCI with objectively observable deficits in these areas and document efficacy on standard neuropsychological testing; (2) assess the effectiveness of the interventions in persons with SCI utilizing global measures of everyday life; (3) evaluate the long-term benefit of treatment. Prior to enrollment in the study protocol, all potential subjects will undergo a 2-part screening: (1) an initial screening examination via telephone during which basic information will be gathered and (2) a detailed, in-person screening that will be completed on if the subject passes the initial screen. Individuals must meet full screening criteria to be eligible for participation.
1,948 studies on the registry are indexed under Spinal Cord Injuries; 505 are open to participants now.
This study's planned enrollment of 104 is above the median of 24 across 1,566 interventional studies indexed under Spinal Cord Injuries.
Browse Spinal Cord Injuries studies →Kessler Foundation is the lead sponsor of 170 studies on the registry; 58 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Experimental group will receive memory retraining exercises administered on a lab top computer twice a week for 5 weeks.
Behavioral: Behavorial; memory exercise
Placebo controlled group will receive placebo memory retraining exercises administered on a lab top computer twice a week for 5 weeks.
Behavioral: Placebo; memory exercise
Processing speed group will receive processing speed training exercises administered on a lab top computer twice a week for 5 weeks.
Behavioral: Behavioral: speed exercises
Placebo controlled group will receive placebo processing speed training exercises administered on a lab top computer twice a week for 5 weeks.
Behavioral: Placebo speed training
Memory training twice a week for 5 weeks.
Placebo Memory training twice a week for 5 weeks
Speed training twice a week for 5 weeks.
Placebo Speed training twice a week for 5 weeks.
California Verbal Learning Test
California Verbal Learning TestPerformance on a memory test using the
Time frame: Assessments will look at change over 6 weeks of treatment and 3 months after completion
SCI Quality of Life Scale
Reports on emotional functioning, memory functioning and quality of life using the SCI Quality of Life Scale, which measures all of these constructs. DVs will be the depression subscale (range: 0-40; lower score is better) and cognitive subscale (range:0-40; higher score is better).
Time frame: Assessments will look at change over 6 weeks of treatment and 3 months after completion
Symbol-Digit Modalities Test (oral form)
Performance on processing speed test, Symbol-Digit Modalities Test (oral form)
Time frame: Assessments will look at change over 6 weeks of treatment and 3 months after completion
This study is completed, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.
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Kessler Foundation