An interventional study of Neurocognitive Testing in Concussion, Brain, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 16 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-04-16.
Sponsored by Mayo Clinic · Not applicable, Interventional, and Basic science
Researchers are trying to determine if the impact of a concussion on the brain is affected by anesthesia and surgery.
All subjects will complete pre and post procedure assessments prior to undergoing a planned surgery/anesthetic standard of care.
530 studies on the registry are indexed under Brain Concussion; 151 are open to participants now.
This study's enrollment of 52 is below the median of 64 across 364 interventional studies indexed under Brain Concussion.
Browse Brain Concussion studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Subjects diagnosed with concussion defined as a clinician-diagnosed disease by the International Classification of Diseases (ICD)-10 due to a head injury with a Glasgow Coma Score ≥13 undergoing a planned surgery/anesthetic standard of care will undergo neurocognitive testing pre and post surgery/anesthetic.
Other: Neurocognitive Testing
Matched subjects without concussion undergoing a planned surgery/anesthetic standard of care, matching for procedural type, sex, age ± 2 years, and adherence to the exclusion criteria will undergo neurocognitive testing pre and post surgery/anesthetic.
Other: Neurocognitive Testing
A comprehensive assessment of neuropsychometric measures to evaluate cognitive functioning.
Wide Range Achievement Test Fourth Edition, WRAT-4
Change in WRAT-4
Time frame: Pre-anesthetic to one week Post-anesthetic
Numeric Pain Scale 0-10
Difference in numeric pain scale between the concussion and non-concussion group. Patients verbally select a value that is in line with the intensity of pain they have experienced in the last 24 hours. Pain Scale is recorded "0" = no pain, "10" = the most pain imaginable.
Time frame: Post-operatively to hospital discharge, up to 10 days.
Oral morphine equivalent of consumed opioids
Difference of post-operative opioid use between the concussion and non-concussion group
Time frame: Post-operatively to hospital discharge, up to 10 days.
Length of hospital stay
Difference between the concussion and non-concussion group
Time frame: Post-operatively to hospital discharge, up to 30 days.
Cognitive Deficits identified by NeuroPsychometric Cognitive Testing
Difference between the concussion and non-concussion group.
Time frame: Pre-anesthetic to one week Post-anesthetic
Sport Concussion Assessment Tool - 5th edition, SCAT-5
The SCAT5 is a standardized tool for evaluating concussions designed for use by physicians and licensed medical professionals. Difference in SCAT5 scores between the concussion and non-concussion group. SCAT5 scores the number of symptoms (0-22) present and the severity of symptoms (0-132).
Time frame: Pre-anesthetic to one week Post-anesthetic
This study is completed, as verified in Apr 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Mayo Clinic