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CompletedNCT03907267Updated Jan 28, 2020

Taurine in Peripartum Cardiomyopathy

A Phase 2/3 interventional study of Taurine Solution and Normal Saline in Peripartum Cardiomyopathy, sponsored by Ain Shams University. Completed at 1 site in Egypt. Open to female participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2020-01-28.

Sponsored by Ain Shams University · Phase 2/3, Interventional, and Treatment

From the registry’s dates

  • Registered 4 years 3 months after the study started (first participant enrolled Jan 2015, registered Apr 2019).
Phase
Phase 2/3
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 40 Years
Sex
Female
01

Study summary

Taurine as an adjunct for early left ventricular recovery in peripartum cardiomyopathy

02

Conditions studied

  • Peripartum Cardiomyopathy

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03

In context

Cardiomyopathies

1,176 studies on the registry are indexed under Cardiomyopathies; 287 are open to participants now.

This study's enrollment of 40 is below the median of 51 across 609 interventional studies indexed under Cardiomyopathies.

Browse Cardiomyopathies studies →

Lead sponsor

Ain Shams University is the lead sponsor of 1,876 studies on the registry; 423 are open to participants now.

Of its 32 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Peripartum Cardiomyopathy

Exclusion criteria

Exclusion Criteria:

  • Other identifiable cause for heart failure
  • low LVEF ≤ 25%
  • sepsis
  • autoimmune disease
  • severe chronic disease
  • malignancy
05

Study design

Phase
Phase 2 / Phase 3
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Taurine

    Drug: Taurine Solution

  • Placebo comparator
    Saline

    Dietary Supplement: Normal Saline

Interventions

  • DrugTaurine Solution

    Taurine Solution

  • Dietary supplementNormal Saline

    Normal Saline

06

What researchers measure

Primary outcomes

  1. improvement of the left ventricular ejection fraction >10 %

    improvement of the left ventricular ejection fraction \>10 %

    Time frame: 1 week

07

Study locations

1 site
  • Ain Shams University Maternity Hospital
    Cairo, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 28, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03907267
Lead sponsor
Ain Shams University
Responsible party
Mohamed S Sweed, MD (Principal Investigator, Ain Shams University) — Principal investigator
First posted
Apr 8, 2019
Start date
Jan 1, 2015
Primary completion
Dec 1, 2019
Completion
Jan 1, 2020
Last update
Jan 28, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.

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