An interventional study of functional Magnetic Resonance Imaging in Neurologic Signs, sponsored by Hospices Civils de Lyon. Withdrawn. Open to participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-02-25.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Basic science
Little is known about the exact role of feedback in cortical processing. Hypotheses on its function range from attentional control to the transmission of Bayesian priors in the interpretation of sensory events, such as in the theory of Predictive Coding. Recent advances in identification of functional signatures of feedback and feedforward signal, as well as additional techniques based on causal relations in signal processing open a unique methodology for probing such processes in awake and behaving organisms and testing these theories and more generally the hierarchical processing between cortical areas.
The objective of this project is to study feedback and feedforward relations and localization in the well established pathways between cortical areas V1 and Medial Temporal (MT) that have been implicated in early integration processes in motion perception.
198 studies on the registry are indexed under Neurologic Manifestations; 67 are open to participants now.
Browse Neurologic Manifestations studies →Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.
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Exclusion Criteria:
25 healthy subjects with a normal/corrected vision fitting to all of the inclusion/exclusion criteria. All the subjects will be tested on the same visual stimuli, leading to intrasubject comparison analyses of functional magnetic resonance imaging (fMRI) activity between conditions.
Device: functional Magnetic Resonance Imaging
In a 2-hour session, the subject we be shown different control and experimental conditions (all being visual stimuli) in perceptive tasks.
Non-invasive Blood oxygenation level dependent (BOLD) fMRI activity
Blood oxygenation level dependent (BOLD) imaging is the standard technique used to generate images in fMRI studies, and relies on regional differences in cerebral blood flow to delineate regional activity. This non-invasive technic is not inducing any particular risk. The non invasive BOLD fMRI activity will be recorded in healthy subjects during a task of visual perception.
Time frame: At inclusion
No study locations are listed for this record.
This study is withdrawn, as verified in Feb 2021. You cannot join it, but the record below documents what was studied.
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Hospices Civils de Lyon