A Phase 4 interventional study of Control and 0.5% concentration of PVP-I in Impacted Third Molar Tooth, sponsored by Cansu Gül Koca. Completed. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-03-28.
Sponsored by Cansu Gül Koca · Phase 4, Interventional, and Treatment
The aim of the present study was to evaluate the effects of different concentrations of povidone iodine (PVP-I) on postoperative swelling and trismus when used as a coolant and irrigation solution during the surgical removal of impacted mandibular third molars.
195 studies on the registry are indexed under Tooth, Impacted; 20 are open to participants now.
This study's enrollment of 80 is above the median of 53 across 164 interventional studies indexed under Tooth, Impacted.
Browse Tooth, Impacted studies →This is the only study on the registry with Cansu Gül Koca as lead sponsor.
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Exclusion Criteria:
Control Group: Intraoperative irrigation with saline solution only.
Procedure: Control
Experimental Group: Intraoperative irrigation with 0.5% concentration of PVP-I solution.
Procedure: 0.5% concentration of PVP-I
Experimental Group: Intraoperative irrigation with 1% concentration of PVP-I solution.
Procedure: 1 % concentration of PVP-I
Experimental Group: Intraoperative irrigation with 3% concentration of PVP-I solution.
Procedure: 3 % concentration of PVP-I
During the third molar extraction the saline solution will be used in the control group.
During the third molar extraction 0.5% concentration of PVP-I solution will be used in the test group.
During the third molar extraction 1 % concentration of PVP-I solution will be used in the test group.
During the third molar extraction 3 % concentration of PVP-I solution will be used in the test group.
Postoperative Facial Swelling (assessed 3 facial lines (in millimeters) for determination of difference in facial contours before and after surgery)
For the assessment of facial swelling, three facial lines (in milimeters) were measured with a digital tape on the operated side using following (4) landmarks: the external canthus of the eye, the gonion angle, the lower border of the tragus, soft pogonion and the mouth commissure Facial Lines between: 1. the external canthus of the eye- the gonion angle 2. the lower border of the tragus-the mouth commissure 3. the lower border of the tragus- soft pogonion
Time frame: Preoperative (on the day of surgery)- postoperative 2nd day-postoperative 7th day
Postoperative Trismus (difference in interincisal distance at the maximal mouth opening (in millimeters) before and after surgery)
The degree of trismus was assessed by measuring the distance between upper and lower incisal borders of the central incisors with a digital caliper.
Time frame: Preoperative (on the day of surgery)- postoperative 2nd day-postoperative 7th day.
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This study is completed, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.
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