An interventional study of BIPAP, Intelligent automatic mode defined by assured volume with pressure support and BIPAP, manual tritration. in Hypoxemic Respiratory Failure and Hypercapnic Respiratory Failure, sponsored by Hospital Clinic of Barcelona. Completed at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-02-29.
Sponsored by Hospital Clinic of Barcelona · Not applicable, Interventional, and Treatment
To evaluate the polysomnographic performance of an automatic ventilatory mode compared with the gold standard (manual polysomnographic titration) to adjust chronic non-invasive ventilation by means of a randomized cross-over study.
Prospective randomized crossover study in 26 patients with chronic non-invasive ventilation (NIV) criteria, comparing the NIV titration with polysomnography vs an automatic mode of ventilation. It will be compared with clinical parameters of ventilation, blood analysis and inflammation reactants as well as evaluating the patient's comfort after each mode.
1,650 studies on the registry are indexed under Respiratory Insufficiency; 297 are open to participants now.
This study's enrollment of 26 is below the median of 55 across 1,042 interventional studies indexed under Respiratory Insufficiency.
Browse Respiratory Insufficiency studies →Hospital Clinic of Barcelona is the lead sponsor of 319 studies on the registry; 55 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Inclusion Criteria: chronic respiratory failure
Exclusion Criteria:
Manual titration of non-invasive mechanical ventilation using polysomnography and randomized
Device: BIPAP, manual tritration.
Automatic titration of the non-invasive mechanical ventilation using the same device in an automatic mode with assured volume and pressure support.
Device: BIPAP, Intelligent automatic mode defined by assured volume with pressure support
Correction of night ventilation through an automatic mode of ventilation with assured volume with pressure support
Correction of night ventilation through a manual titration of non-invasive mechanical ventilation using polysomnography.
Partial pressure of carbon dioxide (PaCO2)
Measure levels after each polysomnography using arterial blood gases
Time frame: two weeks
Partial pressure of oxygen (PaO2)
Measure levels after each polysomnography using arterial blood gases
Time frame: two weeks
Oxygen saving time below 90% (CT90%)
Assess the polysomnography reduction in CT90% through the night study.
Time frame: one month
This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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Hospital Clinic of Barcelona