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Status unknownNCT03845556Updated Feb 19, 2019

Clinical Study of Titrating PEEP of Different Methods on Right Heart Function

An observational study in ARDS, Human, sponsored by Southeast University, China. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-02-19.

Sponsored by Southeast University, China · Observational

The sponsor has not verified this record recently (last verified Feb 2019), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
30
Ages
18 Years to 80 Years
Sex
All
01

Study summary

To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .

Read the detailed description

30 patients who diagnosed as ARDS were included in this study.Then set PEEP with respectively ARDS net 、EIT and Esophageal Pressure in Breathing Machine . Recorded diameter of right and left ventricular TAM TAPSE pulmonary artery pressure.Objective to evaluate the correlation between the level of PEEP in three methods and the right heart function and pulmonary artery pressure in ARDS patients .

02

Conditions studied

  • ARDS, Human
03

In context

Respiratory Distress Syndrome

1,597 studies on the registry are indexed under Respiratory Distress Syndrome; 312 are open to participants now.

This study's planned enrollment of 30 is below the median of 100 across 540 observational studies indexed under Respiratory Distress Syndrome.

Browse Respiratory Distress Syndrome studies →

Lead sponsor

Southeast University, China is the lead sponsor of 164 studies on the registry; 44 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Population admitted to ICU of Zhongda hospital，diagnosed of medium or serious ARDS。

Inclusion criteria

  • Patients admitted to ICU diagnosed of modecate to severe ARDS (Berlin criteria)
  • Patients age between 18 years old and 80 years

Exclusion criteria

Exclusion Criteria:

  • Patients with chronic respiratory diseases such as COPD.
  • Ventilated because of oesophageal surgery in the previous 12months.
  • Patients who cannot obtain clear ultrasound images due to thoracic surgery ,massive pleural effusion.
  • Oesophageal bleeding in previous 30 days history of oesophageal varices.
  • Facial trauma and surgery.
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
30 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes
06

What researchers measure

Primary outcomes

  1. the function of right heart and pulmonary artery pressure

    Systolic Pulmonary Artery Pressure TAPSE or Tricuspid Annular Motion orTricuspid annular plane systolic excursion or right ventricular diameter or right left ventricular diameter ratio in diffrient PEEP

    Time frame: 2018.4-2019.3

07

Study locations

1 of 1 sites recruiting
  • Zhongda Hospital
    Nanjing, Jiangsu 210009, China
    • Feng Mei Guo, Dr · Contact · 13813841261@139.com · 13813841261
    • FengMei Guo, Dr · Principal investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 19, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT03845556
Lead sponsor
Southeast University, China
Collaborators
Zhongda Hospital
Responsible party
Chun Pan (Clinical Professor, Southeast University, China) — Principal investigator
First posted
Feb 19, 2019
Start date
Aug 4, 2018
Primary completion
Mar 30, 2019 (estimated)
Completion
Mar 30, 2019 (estimated)
Last update
Feb 19, 2019

Study contacts

Dutong Yue, Dr
Contact
1475008526@qq.com
15051887681
GuoFeng Mei, Dr
Contact
13813841261@139.com
13813841261
Chun Pan, Dr
principal investigator · southeast university

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.

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Discussion

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