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CompletedNCT03821155Updated Jul 29, 2022

Does Vestibular Rehabilitation Significantly Improve the Level of Vestibular Function Following Vestibular Neuritis?

An interventional study of Vestibular rehabilitation and Corticosteroid in Vestibular Neuritis, sponsored by Aalborg University Hospital. Completed at 1 site in Denmark. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-07-29.

Sponsored by Aalborg University Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

To investigate which treatment option (corticosteroid treatment alone or combined corticosteroid treatment and vestibular rehabilitation) is the most effective in patients diagnosed with vestibular neuritis.

Read the detailed description

Patients diagnosed with vestibular neuritis will we consider for enrollment. Each patient will undergo randomization for a specific treatment.

02

Conditions studied

  • Vestibular Neuritis

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Keywords

  • Vestibular Neuritis
  • SHIMP (suppressing head impulse paradigm)
  • SVV (subjective visual vertical)
  • Vestibular rehabilitation
  • Prednisolone
  • v-HIT (video head impulse test)
  • Vestibular Neuronitis
03

In context

Vestibular Neuronitis

34 studies on the registry are indexed under Vestibular Neuronitis; 4 are open to participants now.

This study's enrollment of 50 is close to the median of 50 across 27 interventional studies indexed under Vestibular Neuronitis.

Browse Vestibular Neuronitis studies →

Lead sponsor

Aalborg University Hospital is the lead sponsor of 198 studies on the registry; 41 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Age above 18 years of age
  2. Medical history compatible with vestibular neuritis
  3. Verification of vestibular neuritis with positive romberg test, pathological v-HIT and horizontal nystagmus with a rotatory component.

Exclusion criteria

Exclusion Criteria:

  1. Former medical history with vestibular dysfunction
  2. Medical history or objective signs of cochlear dysfunction before, during or after onset of vestibular neuritis
  3. Onset of symptoms 14 days before recruitment to the study
  4. Focal neurological symptoms/signs
  5. to prednisolone treatment
  6. Problem with participating in vestibular rehabilitation due to muscular-skeletal disease ect.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
50 participants (actual)

Study arms

  • Active comparator
    Neuritis vestibularis (group 1)

    Corticosteroid ("prednisolone")

    Drug: Corticosteroid

  • Experimental
    Neuritis vestibularis (group 2)

    Corticosteroid ("prednisolone") + vestibular rehabilitation

    Other: Vestibular rehabilitation · Drug: Corticosteroid

Interventions

  • OtherVestibular rehabilitation

    Specialized physical therapy aimed at restoring balance

  • DrugCorticosteroid

    Prednisolone

06

What researchers measure

Primary outcomes

  1. Suppressing head impulse paradigm (SHIMP)

    SHIMP equipment will objectively quantify change of vestibular function.

    Time frame: 6 month

  2. Subjective visual vertical (SVV)

    SVV test will objectively quantify the experienced spatial orientation as an indicator of visual and vestibular otolithic function

    Time frame: 6 month

  3. Video head impulse test (v-HIT)

    v-HIT equipment will objectively quantify change of vestibular function.

    Time frame: 6 month

  4. Dizziness handicap inventory (DHI) questionnaire

    Fulfillment of the questionnaire "Dizziness Handicap Inventory" (DHI) will quantify the level of experienced vertigo.

    Time frame: 6 month

07

Study locations

1 site
  • Department of Otolaryngology, Head & Neck Surgery and Audiology
    Aalborg, North Denmark Region 9000, Denmark
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 29, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03821155
Responsible party
Dan Dupont Hougaard (MD, Assistant Professor, Aalborg University Hospital) — Principal investigator
First posted
Jan 29, 2019
Start date
Feb 1, 2019
Primary completion
Jul 1, 2021
Completion
Jan 1, 2022
Last update
Jul 29, 2022

Study contacts

Dan D Hougaard, MD
principal investigator · Aalborg University Hospital
Martin H Wolder, MS
principal investigator · Aalborg University Hospital

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jul 2022. You cannot join it, but the record below documents what was studied.

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