An interventional study of Pressure Controlled Ventilation and Volume Controlled Ventilation in Prostate Cancer, sponsored by Istanbul University. Status unknown at 1 site in Turkey. Open to male participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2019-02-27.
Sponsored by Istanbul University · Not applicable, Interventional, and Diagnostic
This study will be performed in robotic assisted laparoscopic radical prostatectomy patients in Cerrahpasa Medical Faculty Monoblock Operating Room. Since robot-assisted laparoscopic radical prostatectomy is a surgical procedure which requires long-term mechanical ventilation, excessive trendelenburg position (30-45 °) and pneumoperitoneum; these interventions may lead to respiratory complications such as ventilation difficulty and aeration loss in patients. Nowadays, lung ultrasonography has been used in anesthesia practice and intensive care units in order to determine lung aeration loss. In this study, the investigators aimed to compare the possible aeration loss in lung parenchyma during pressure controlled ventilation and volume controlled ventilation which are frequently used in anesthesia practice in patients undergoing robotic radical prostatectomy.
6,370 studies on the registry are indexed under Prostatic Neoplasms; 1,400 are open to participants now.
This study's planned enrollment of 72 is above the median of 58 across 4,822 interventional studies indexed under Prostatic Neoplasms.
Browse Prostatic Neoplasms studies →Istanbul University is the lead sponsor of 496 studies on the registry; 79 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 1 (20%) have results posted.
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Inclusion Criteria: 18-75 age
Exclusion Criteria:
Patients undergoing pressure controlled ventilation
Other: Pressure Controlled Ventilation
Patients undergoing volume controlled ventilation
Other: Volume Controlled Ventilation
Patients will be ventilated with a pressure level which supplies a tidal volume corresponding 8ml/kg, 12 breaths per minute, 1/2 inspiration/expiration ratio and %40 Fraction of Inspired Oxygen . These ventilator settings can be changed in order to adjust end tidal carbon dioxide and oxygen saturation levels.
Patients will be ventilated with a tidal volume which corresponds 8ml/kg, 12 breaths per minute, 1/2 inspirastion/expiration ratio and %40 Fraction of Inspired Oxygen . These ventilator settings can be changed in order to adjust end tidal carbon dioxide and oxygen saturation levels.
The difference between LUS Scores at T5 in patients ventilated with VCV and PCV
Lung Ultrasonography will be applied to patients after surgery in the recovery room at T5. Two different groups' LUS scores will be calculated and compared.
Time frame: (T5) 60 minutes after patients come to the recovery room.
The difference between LUS Scores at T2 in patients ventilated with VCV and PCV
Lung Ultrasonography will be applied to patients after intubation. Two different groups' LUS scores will be calculated and compared.
Time frame: (T2) 5 minutes after intubation
The difference between LUS Scores at T3 in patients ventilated with VCV and PCV
Lung Ultrasonography will be applied to patients at Trendelenburg position after the surgical prosedure is finished. Two different groups' LUS scores will be calculated and compared.
Time frame: (T3) 5 minutes after the surgical procedure is finished
The difference between LUS Scores at T4 in patients ventilated with VCV and PCV
Lung Ultrasonography will be applied to patients at supin position after the surgical prosedure is finished. Two different groups' LUS scores will be calculated and compared.
Time frame: (T4) 5 minutes after taking the patient to supin position
Plan to share: Undecided
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Istanbul University