An interventional study of Cytochalasin B use in ICSI handling medium in Infertility, sponsored by Ibn Sina Hospital. Completed at 1 site in Egypt. Open to female participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2019-08-07.
Sponsored by Ibn Sina Hospital · Not applicable, Interventional, and Prevention
Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Cytochalasin B serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Cytochalasin B during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes,
2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.
This study's enrollment of 987 is above the median of 120 across 1,698 interventional studies indexed under Infertility.
Browse Infertility studies →Ibn Sina Hospital is the lead sponsor of 28 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Other: Cytochalasin B use in ICSI handling medium
A medium with in-house supplementation of Cytochalasin B to decrease oocyte degeneration after ICSI and improve survival rate
oocyte survival rate
number of survived oocyte after intracytoplasmic sperm injection
Time frame: 6 days of culture
fertilization rate
number of fertilized oocytes per metaphase II injected
Time frame: 6 days of culture
blastocyst formation rate
number of formed blastocyst per fertilized oocyte
Time frame: 6 days of culture
embryo utilization rate
number of embryo transferred added to number of those cryopreserved per fertilized oocyte
Time frame: 6 days of culture
clinical pregnancy rate
number of women with a heartbeat at week 4 or more after embryo transfer
Time frame: three months
ongoing pregnancy rate
number of women with continued pregnancy after twelve weeks of gestation
Time frame: four months
Plan to share: No
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This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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Ibn Sina Hospital