An interventional study of Human embryo culture in Infertility, sponsored by Ibn Sina Hospital. Completed at 3 sites in Egypt. Open to female participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2020-06-11.
Sponsored by Ibn Sina Hospital · Not applicable, Interventional, and Other
Humidity for human embryo culture has been raised as essential with advantageous effect on clinical pregnancy and ongoing pregnancy after ICSI compared with a dry incubator. Whether the deleterious effect of dry culture would have an extended effect reaches the live birth rate needs to be examined. This RCT is to examine the effect of dry and humidified culture on live birth rates after ICSI.
2,085 studies on the registry are indexed under Infertility; 357 are open to participants now.
This study's enrollment of 1,837 is above the median of 135 across 1,412 interventional studies indexed under Infertility.
Browse Infertility studies →Ibn Sina Hospital is the lead sponsor of 28 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Embryo culture after in vitro fertilization in incubator with no humidity
Other: Human embryo culture
Embryo culture after in vitro fertilization in incubator with humidity
humidifed or dry incubator
Live birth rate
Viable neonate after 30 weeks of gestation per initiated cycle
Time frame: 30 weeks
Cumulative live birth rate
Viable neonate after 30 weeks of gestation after one fresh and/or one frozen-warmed transfer per initiated cycle
Time frame: One year
Ongoing pregnancy rate
Continued pregnancy after 12 weeks of gestation per initiated cycle
Time frame: 12 weeks of gestation
Cumulative ongoing pregnancy rate
Continued pregnancy after 12 weeks of gestation per initiated cycle within one year of randomization
Time frame: 12 weeks of gestation
Clinical pregnancy rate
Ultrasound detect heartbeat after 7 weeks of gestation per initiated cycle
Time frame: 7 weeks of gestation
Cumulative clinical pregnancy rate
Ultrasound detect heartbeat after 7 weeks of gestation per initiated cycle within one year of randomization
Time frame: 7 weeks of gestation
Implantation rate
Number of sacs with a heartbeat per number of embryo transferred
Time frame: 7 weeks of gestation
Cumulative implantation rate
Number of sacs with a heartbeat per number of embryo transferred within one year of randomization
Time frame: 7 weeks of gestation
Ongoing implantation rate
Number of sacs with a heartbeat per number of embryo transferred
Time frame: 12 weeks of gestation
Cumulative ongoing implantation rate
Number of sacs with a heartbeat per number of embryo transferred within one year of randomization
Time frame: 12 weeks of gestation
Preterm birth rate
number of babies born before 37 weeks of gestation per total birth
Time frame: 37 weeks
Very preterm birth
number of babies born before 32 weeks of gestation per total birth
Time frame: 32 weeks
Low birth weight rate
number of babies with \< 2500 gm per total birth
Time frame: 40 weeks of gestation
Fertilization rate
fertilized oocytes with two pronuclei per Metaphase II injected
Time frame: 6 days of culture
Cleavage rate
Cleaved embryo per fertilized oocyte
Time frame: 6 days of culture
Rate of high-quality day-3 embryos
Embryos with seven or eight blastomeres of appropriate-size, and \< 10% fragmentation by volume per fertilized oocyte
Time frame: 6 days of culture
Blastocyst formation rate
Formed blastocyst on day 5/6 from fertilized oocytes
Time frame: 6 days of culture
Rate of high-quality blastocyst
Blastocysts ≥ 3.1.1 grade per fertilized oocyte
Time frame: 6 days of culture
Rate of utilizable blastocyst
Transferred and cryopreserved blastocysts from fertilized oocytes
Time frame: 6 days of culture
Plan to share: No
No publications or documents are linked to this record.
Ran from Feb 2019 to primary completion in Mar 2020, 13 months.
Of 385 non-industry interventional studies with no phase under Infertility, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 46. This study's 13 months is below that.
Counting every sponsor, half of 416 studies reached it within 24 months; a quarter within 10 and three quarters within 43.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jun 2020. You cannot join it, but the record below documents what was studied.
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Ibn Sina Hospital