An observational study in Intracranial Hypertension and Optic Nerve Sheath Diameter, sponsored by Hospital Dr. Miguel Pérez Carreño. Completed at 1 site in Venezuela. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2018-11-08.
Sponsored by Hospital Dr. Miguel Pérez Carreño · Observational
Measurement of the diameter of the sheath of the optic nerve in patients hospitalized in intensive care, with increased intracranial pressure (> 20mmHg) as a substitute measure for diagnosis and follow-up before and after different non-invasive strategies.
Three groups were created in which, through strategies already proven and non-invasive (mannitol, hypertonic solution 7.5% NaCl, reverse trendelenburg) to decrease the intracranial pressure, the optic nerve diameter measurement was performed and simultaneously the investigators monitored intracranial pressure through an intraventricular catheter continuously to determine if both correspond
185 studies on the registry are indexed under Intracranial Hypertension; 45 are open to participants now.
This study's enrollment of 90 is above the median of 60 across 80 observational studies indexed under Intracranial Hypertension.
Browse Intracranial Hypertension studies →This is the only study on the registry with Hospital Dr. Miguel Pérez Carreño as lead sponsor.
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Patients hospitalized in the intensive care unit of the Dr. Migel Pérez Carreño hospital with increased intracranial pressure of traumatic or non-traumatic etiology.
Exclusion Criteria:
both optic nerve sheath diameter (the posterior 3mm of the papilla) before and after received 0.5gr/kg 20% mannitol
Diagnostic Test: optical nerve sheet diameter
both optic nerve sheath diameter (the posterior 3mm of the papilla) before and after received 1.5 ml/kg 7.5% NaCl solution
Diagnostic Test: optical nerve sheet diameter
both optic nerve sheath diameter (the posterior 3mm of the papilla) before and after patients were positioned on reverse Trendelenburg position 30 degrees higher than the feet
Diagnostic Test: optical nerve sheet diameter
The ONSD in each eye was measured vertically and horizontally 3 mm behind the optic disc, with the two values averaged. No pressure was applied to the orbit. At each time point, measurements were taken within 5 min. The measurements were made before (T1) and after some of the strategies according to group 30 min (T2), 60 min (T3), and 90 min (T4).
Optic nerve sheet diameter
The optic nerve sheet diameter in each eye was measured vertically and horizontally 3 mm behind the optic disc, with the two values averaged
Time frame: immediately before administering the treatment according to the group and every 30 minutes after administering the treatment until 90 min.
Plan to share: Undecided
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