An interventional study of Power Training Session in Hypertension, sponsored by Hospital de Clinicas de Porto Alegre. Completed at 1 site in Brazil. Open to participants aged 60 Years to 75 Years. Per ClinicalTrials.gov, last updated 2021-01-14.
Sponsored by Hospital de Clinicas de Porto Alegre · Not applicable, Interventional, and Treatment
The main purpose of the present study was to evaluate the effect of a power training session on office and 24h ambulatory blood pressure in older adults with hypertension. As secondary outcomes, the investigators compared post-exercise hypotension, BP variability, and endothelial function between older men and women with hypertension.
The working hypothesis was that a single bout of power exercise would decrease both office and 24 h BP in comparison to a non-exercising control session and men and women would respond differently after a power training session.
Participants randomly performed two experimental sessions: power exercise training (PT) and non-exercising control at seated rest (Con). They maintained their current antihypertensive medications throughout the trial. Each session was composed of 20 min of rest in the supine position, 40 min of PT or Con protocols, and 60 min of rest in supine position after protocols. The PT was composed of 3 sets of 8-10 repetitions of 5 exercises performed in the following order: leg press, bench press, knee extension, upright row, and knee flexion, using an intensity corresponding to 50 % of 1-RM and two-minute intervals between sets and exercises. The concentric phase of exercises during each repetition was performed "as fast as possible" while the eccentric phase lasted 1-2 seconds. During the Con, the participants remained seated rest on the same exercise machines, but without any exercise. Standardized office BP was performed before and during the first hour (in intervals of 15 min) after exercise and control sessions. Together with the office BP evaluation in the pre and post sessions, the endothelium-dependent brachial vascular function was evaluated using Flow-mediated dilation. Afterwards, participants underwent 24h ambulatory BP monitoring..
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This study's enrollment of 24 is below the median of 90 across 4,995 interventional studies indexed under Hypertension.
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Exclusion Criteria:
Control session without any exercise. The participants remained in seated rest throughout 40 min
The power training session lasted 40 min, in which the participants performed a resistance exercise session using high velocity contractions during the exercises characterizing a power training session
Behavioral: Power Training Session
3 sets of 8-10 repetitions of 5 exercises performed in the following order: leg press, bench press, knee extension, upright row, and knee flexion, using an intensity corresponding to 50 % of 1-RM and two-minute intervals between sets and exercises. The concentric phase of exercises during each repetition was performed "as fast as possible" while the eccentric phase lasted 1-2 seconds.
Ambulatory Blood Pressure Monitoring
Mean 24-h, day-time, night-time of blood pressure in mmHg will be assessed after each experimental session (power training session and control session)
Time frame: 24 hours after control and power training exercise session
Office Systolic Blood Pressure
Systolic blood pressure in mmHg will be measured using automatic oscillometric before and after each experimental session throughout one hour
Time frame: 60 minutes after control and power training exercise session
Office Diastolic Blood Pressure
Diastolic blood pressure in mmHg will be measured using automatic oscillometric before and after each experimental session throughout one hour
Time frame: 60 minutes after control and power training exercise session
Endothelial Function
Flow-mediated dilatation (FMD) assessed through high resolution ultrasonography before and after each experimental session throughout one hour
Time frame: 60 minutes after control and power training exercise session
Blood Pressure Variability
Systolic and diastolic BP values obtained in the 24-hour ambulatory blood pressure monitoring, with valid measures included in a programmed software to calculate the average real variability of these measures.
Time frame: 24 hours after control and power training exercise session
Sex Differences in Ambulatory Blood Pressure Monitoring, Office Blood Pressure, Endothelial Function and Blood Pressure Variability
Time frame: 60 minutes and 24 hours after control and power training exercise session
Plan to share: Undecided
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Hospital de Clinicas de Porto Alegre