An observational study in Pulmonary MAC, Energy Metabolism and Emaciation, sponsored by National Hospital Organization Minami Kyoto Hospital. Completed at 1 site in Japan. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2021-12-28.
Sponsored by National Hospital Organization Minami Kyoto Hospital · Observational
We aim to examine energy metabolism in patients with pulmonary MAC and clarify the causes of emaciation. We will also investigate the following: the relation between energy metabolism and degree of pulmonary MAC progression; relations among hospitalization, mortality rate, and time-course of changes in energy metabolism; and factors that affect energy metabolism.
Patients with pulmonary MAC with a lower BMI than healthy individuals also have a significantly poorer prognosis than those of normal weight. Emaciation in such patients is thought to be caused by destruction of lung structure from disease progression and an increased resting metabolic rate caused by the increased load from breathing; however, causes of emaciation and details of energy metabolism in these patients have not been studied.
Elucidating details of energy metabolism and causes of emaciation in patients with pulmonary MAC could provide the basis for improvement in nutritional status and activities of daily living through early nutrition therapy and rehabilitation. We propose to clarify the following:
Energy metabolism in patients with pulmonary MAC, including resting metabolic rate, calorie intake and consumption, and hormonal secretions.
Relation between energy metabolism and degree of pulmonary MAC progression.
72 studies on the registry are indexed under Mycobacterium avium-intracellulare Infection; 8 are open to participants now.
This study's enrollment of 105 is close to the median of 100 across 12 observational studies indexed under Mycobacterium avium-intracellulare Infection.
Browse Mycobacterium avium-intracellulare Infection studies →National Hospital Organization Minami Kyoto Hospital is the lead sponsor of 7 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Petients with pulmonary MAC
Exclusion Criteria:
Relation between energy balance and pulmonary MAC severity
Time frame: Three years
Relation between inflammation (CRP et.) and pulmonary MAC severity
Time frame: Three years
Relation between bone mineral density and pulmonary MAC severity
Time frame: Three years
Relation between hormone secretion and pulmonary MAC severity
Time frame: Three years
Relation between pulmonary function and pulmonary MAC severity
Time frame: Three years
This study is completed, as verified in Dec 2021. You cannot join it, but the record below documents what was studied.
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National Hospital Organization Minami Kyoto Hospital