An interventional study of Intact cod protein from fillet and Intact cod protein from residual material in Overweight and Obesity and Healthy, sponsored by University of Bergen. Completed at 1 site in Norway. Open to participants aged 20 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-01-04.
Sponsored by University of Bergen · Not applicable, Interventional, and Treatment
A high intake of fish is associated with positive health effects, including prevention and treatment of chronic non-communicable diseases, such as cardiovascular diseases (CVDs) and type 2 diabetes. These health effects have traditionally been attributed to the omega-3 fatty acids in fatty fish, but recent studies have suggested that also fish proteins may improve biomarkers of metabolic disease. Intake of cod fillet have previously shown beneficial effects on blood lipids, glucose regulation and body composition in adults with overweight or obesity. Health effect of cod residual material from fillet production (i.e., head, backbone, skin, cutoffs and entrails) have so far not been investigated, but residuals from other fish species have shown promising effects on glucose regulation in rats. The main aim of the current study is to investigate the effects of protein from cod fillet and cod residuals on serum lipids, glucose regulation and inflammatory markers in healthy overweight or obese adults.
3,670 studies on the registry are indexed under Overweight; 849 are open to participants now.
This study's planned enrollment of 100 is above the median of 73 across 3,175 interventional studies indexed under Overweight.
Browse Overweight studies →University of Bergen is the lead sponsor of 141 studies on the registry; 19 are open to participants now.
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Exclusion Criteria:
Dietary supplement: intact cod protein from fillet, 8 g protein daily for 8 weeks
Dietary Supplement: Intact cod protein from fillet
Dietary supplement: intact cod protein from residual material, 8 g protein daily for 8 weeks
Dietary Supplement: Intact cod protein from residual material
Control group receive tablet containing fillers and no proteins
Dietary Supplement: Control
Intact cod protein from fillet 8 g protein daily for 8 weeks
Intact cod protein from residual material, 8 g protein daily for 8 weeks
Control group receive tablet containing fillers
Biomarkers related to lipid metabolism
Lipids will be measured in fasting serum samples
Time frame: 8 weeks
Biomarkers related to glucose regulation
Glucose, insulin and GLP-1 and will be measured in serum/plasma sampled in fasting and postprandial conditions.
Time frame: 8 weeks
Inflammatory markers
Cytokines will be measured in fasting serum/plasma
Time frame: 8 weeks
Body composition
Percent body fat will be measured using bioimpedance
Time frame: 8 weeks
Plan to share: No
This study is completed, as verified in Jan 2022. You cannot join it, but the record below documents what was studied.
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University of Bergen