An observational study in Gender and Early Adolescent Behavior, sponsored by Texas Tech University. Completed at 1 site in United States. Open to participants aged 10 Years to 12 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-10-25.
Sponsored by Texas Tech University · Observational
Risk-taking in early adolescence have has been found to be normative and even formative as it might fulfill the youth's needs to experiment different sensations, make independent decisions and learn from their consequences. Several theoretical models have suggested that male and female adolescents differ in risk-taking as a product of individual/contextual factors and neocortical functioning; however, the neurophysiological and neuropsychological correlates of those differences continue to be underexplored. Informed by Evolutionary Neuroandrogenic Theory, the investigators examine the links between gender, risk-proneness, gratification delay, self-control, self-efficacy, executive functions and neurophysiological-neuroanatomical correlates in early adolescents (age 10-12 years). Participants (N=24; 50% females) will complete behavioral measurements on study constructs and perform neuropsychological tests using fMRI scanning (e.g., Go/NoGo continuous performance, stop-signal reaction time, NIH Cognition Battery, delay discounting). Female and male groups will be compared on all outcome measures.
Texas Tech University is the lead sponsor of 82 studies on the registry; 11 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The study population will consist of healthy early adolescent (age 10-12 years) male and female subjects
Exclusion Criteria:
Other: The study is an observational cross sectional study
Other: The study is an observational cross sectional study
An intervention will not be performed
Female vs. Male differences of fMRI BOLD responses for SSRT Stop Signals
Female vs. male differences of functional magnetic resonance imaging reactivity of the whole brain while performing a Stop Signal Reaction Time Task
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. Male differences of fMRI BOLD responses in a Go-NoGo CPT
Female vs. male differences of functional magnetic resonance imaging reactivity of the whole brain while performing a Go-NoGo Continuous Performance Task
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. Male differences of brain structural connectivity
Female vs. male differences of brain structural connectivity as measured by diffusion tensor imaging and analyzed using tract-based spatial statistics
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. Male differences of brain structure
Female vs. male differences of brain structure as determined by voxel based morphometry of structural magnetic resonance imaging data
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in delay discounting
Female vs. male differences in delay discounting as measures using a delay discounting task presented on a laptop computer
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in stop signal delay
Female vs. male differences in stop signal delay of a stop signal reaction time task performed in the magnetic resonance imaging scanner
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in reaction times of correct Go responses
Female vs. male differences in reaction times of correct Go responses performed in a Go-NoGo continuous performance task performed in the magnetic resonance imaging scanner
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in commission errors in a Go-NoGo CPT
Female vs. male differences commission errors in a Go-NoGo continuous performance task performed in the magnetic resonance imaging scanner
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in Flanker Inhibitory Control and Attention Test
Female vs. male differences in Flanker Inhibitory Control and Attention Test of the NIH Toolbox Cognition Battery
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in Dimensional Change Card Sort Test
Female vs. male differences in Dimensional Change Card Sort Test of the NIH Toolbox Cognition Battery
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in Pattern Comparison Processing Speed Test
Female vs. male differences in Pattern Comparison Processing Speed Test of the NIH Toolbox Cognition Battery
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in risk-proneness
Female vs. male differences in risk-proneness as measured by Impulsive Sensation Seeking Scale adapted by Raffaelli and Crocket (2003)
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in sensation seeking
Female vs. male differences in Brief Sensation Seeking Scale (BSSS) developed by Hoyle et al (2002)
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in gratification delay
Female vs. male differences in abbreviated 10 item Delayed Gratification Inventory (DGI-10) by Romer, Duckworth, Sznitman, \& Park (2010)
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in self-control
Female vs. male differences in Perrone, Sullivan, Pratt, \& Margaryan (2004) measure of self -control adapted from the Longitudinal Study of Adolescent and Adult Health (ADD Health)
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in self-efficacy
Female vs. male differences in General Self-Efficacy Scale (GSE) developed by Schwarzer \& Jerusalem (1995)
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in commission errors in an SSRT
Female vs. male differences in commission errors in a stop signal reaction time task performed in the magnetic resonance imaging scanner
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in omission errors in an SSRT
Female vs. male differences in omission errors in a stop signal reaction time task performed in the magnetic resonance imaging scanner
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in omission errors in a Go-NoGo CPT
Female vs. male differences omission errors in a Go-NoGo continuous performance task performed in the magnetic resonance imaging scanner
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in Picture Sequence Memory Test
Female vs. male differences in Picture Sequence Memory Test of the NIH Toolbox Cognition Battery
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in List Sorting Working Memory Test
Female vs. male differences in List Sorting Working Memory Test of the NIH Toolbox Cognition Battery
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Female vs. male differences in simple visual reaction time
Female vs. male differences in a simple visual reaction time task programmed and presented in PsychoPy software environment on a laptop computer
Time frame: Outcome will be measured on the first study visit (day 1) of each subject. This will also be the only time point of measurement. Outcomes of all recruited subjects within the specified study period will be considered when reporting the outcome measure.
Plan to share: Undecided
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