An interventional study of remifentanil in Intraoperative Awareness, sponsored by West China Second University Hospital. Completed. Open to female participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2018-04-25.
Sponsored by West China Second University Hospital · Not applicable, Interventional, and Prevention
Patients undergoing caesarean delivery under inhalation anaesthesia are at a high risk of awareness, especially in the period before delivery. The investgators assessed the effects of remifentanil on the bispectral index (BIS) in the interval before delivery.
Sixty primipara undergoing elective cesarean delivery were randomly assigned to receive remifentanil 1 μg kg-1 (R1) or 0.5 μg kg-1 (R0.5), or saline (control) over 15 s with induction of anesthesia using propofol 2 mg kg-1 and suxamethonium 1.5 mg kg-1.The investgators assessed the average value of BIS at the time period of before, induction , intubation, skin incision, peritoneum incision , uterine incision , and delivery. The investgators also determined the neonatal Apgar scores, and conducted umbilical artery blood gas analysis.
51 studies on the registry are indexed under Intraoperative Awareness; 7 are open to participants now.
This study's enrollment of 60 is close to the median of 60 across 25 interventional studies indexed under Intraoperative Awareness.
Browse Intraoperative Awareness studies →West China Second University Hospital is the lead sponsor of 37 studies on the registry; 22 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Received remifentanil 1μg/kg when induction of general anesthesia
Drug: remifentanil
Received remifentanil 0.5μg/kg when induction of general anesthesia
Drug: remifentanil
Injected the equal volume normal saline when induction of general anesthesia
the effects of remifentanil on the average value of BIS at the time period of before induction , induction , intubation , skin incision, peritoneum incision, uterine incision, and delivery
Also known as: saline
the effects of remifentanil on the bispectral index (BIS) in the interval before delivery.
the average value of BIS at the time period of before induction, induction , intubation, skin incision, peritoneum incision , uterine incision , and delivery
Time frame: the time of before induction, induction , intubation, skin incision, peritoneum incision , uterine incision , and delivery
incidence of intraoperative awareness
the maternal incidence of intraoperative awareness
Time frame: one day and one week after delivery.
No study locations are listed for this record.
This study is completed, as verified in Apr 2018. You cannot join it, but the record below documents what was studied.
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West China Second University Hospital