CClinicalTrials.gg
CompletedNCT03506880Updated Jun 29, 2023Results posted

Project MADD - NIH Underage DUI and Ride

An interventional study of MADD Materials and Surgeon General Materials in Underage Drinking, Driving Under the Influence and Drinking, Teen, sponsored by Penn State University. Completed at 1 site in United States. Open to participants aged 15 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-06-29.

Sponsored by Penn State University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
2,352
Allocation
Randomized
Ages
15 Years to 18 Years
Sex
All
01

Study summary

Project MADD was designed to attempt to curb the alarming trends related to drunk driving and to move the field forward by testing a brief parent-intervention's ability to change adolescents' drinking, impaired driving, and riding with impaired driver behaviors. The aim of this project is to provide an easy-to-implement and low-cost alternative parent-based intervention that can be widely disseminated to address this important public health problem.

Read the detailed description

Drunk driving is a major public health problem. The National Highway Traffic Safety Administration reported nearly 10,000 people died in alcohol-related crashes in the U.S. in 2014. The problem is further magnified when one considers that each year over 1.3 million drivers in the U.S. are arrested for alcohol-impaired driving. As alarming as these statistics are they pale by comparison to estimates indicating that they only represent 1% of the 121 million self-reported episodes of alcohol-impaired driving among U.S. drivers each year. The proposed research will attempt to curb these alarming trends and move the field forward by conducting a randomized controlled trial testing a brief parent intervention's ability to change adolescents' drinking, impaired driving, and riding with impaired driver behaviors. Prior brief parent-based interventions fro this lab have provided sufficient preliminary evidence of participation, communication, and efficacy for changing under-age drinking to warrant a large-scale comprehensive study. The study will use an extremely rigorous design that meets the Society for Prevention Research Criteria for Efficacy as described in Flay et al., a nationally representative sample assessed at 3-waves (baseline, 6 mo. and 12 mo.) to examine generalizability and sustained effects, and an oversampled Hispanic/Latino subgroup to examine the parent-intervention's potential to reduce a health disparity in an underserved population. The aims are as follows: Aim 1: Evaluate the efficacy of the parent intervention (short and long term); Aim 2: Examine mediators of the PBI that directly influence drinking, impaired driving, and riding with impaired driver behaviors; and Aim 3: Identify moderators to help inform future tailoring and improvement in intervention effectiveness. To the extent that the research is successful, it will provide an easy to implement and low cost alternative that can be widely disseminated to address this important public health problem.

02

Conditions studied

  • Underage Drinking
  • Driving Under the Influence
  • Drinking, Teen

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03

Who can participate

Ages eligible
15 Years to 18 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Parent and teen both consent (forming a dyad testing unit); They are part of GfK's KnowledgePanel pool of participants

Exclusion criteria

Exclusion Criteria:

  • Outside of the teen age range
04

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
2,352 participants (actual)

Study arms

  • Experimental
    MADD Materials

    Handbook developed by MADD and the PI to guide parents in discussing underage drinking, behaviors, and consequences with their teens

    Behavioral: MADD Materials

  • Experimental
    Surgeon General Materials

    Information published by the Surgeon General about teens and drinking

    Behavioral: Surgeon General Materials

  • No intervention
    Control

    TAU

Interventions

  • BehavioralMADD Materials

    Handbook developed by MADD and the PI to guide parents in discussing underage drinking, behaviors, and consequences with their teens

  • BehavioralSurgeon General Materials

    Information published by the Surgeon General about teens and drinking

05

What researchers measure

Primary outcomes

  1. Typical Weekend Drinking (DDQ)

    Typical weekend drinking was assessed using the Daily Drinking Questionnaire (DDQ; Collins et al., 1985), which asked teens to indicate the number of drinks they consumed on a typical Friday and Saturday during the past 6 months. These two items were summed to create the number of typical weekend drinks. Higher scores indicate the teen consumed a higher number of drinks on a typical weekend.

    Time frame: Baseline, 6 month follow-up, and 12 month follow-up

  2. Declining to Ride With Impaired Drivers

    Declining riding with impaired drivers was assessed with two items adapted from Hultgren et al (2018). Teens were asked to indicate the number of times they declined a ride from a driver that consumed alcohol and the number of times they declined a ride from a driver that consumed any drug other than alcohol (e.g., marijuana, opioids) in the past 6 months. Responses were summed to indicate the number of times they declined rides from impaired drivers in the past 6 months. Higher scores indicate the participant declined more rides from impaired drivers.

    Time frame: T4 (12-months post-baseline)

Secondary outcomes

  1. Willingness to Ride in a Car With an Impaired Driver

    Willingness to ride in a car with an impaired driver was assessed with two items adapted from Hultgren et al. (2018). Teens responded using a 7-point scale that ranged from (0) Strongly disagree to (6) Strongly agree on their level of agreement to the following statements, "I am willing to be a passenger in a vehicle when the driver has consumed alcohol." and "I am willing to be a passenger in a vehicle when the driver has consumed any drug other than alcohol (e.g., marijuana, ecstasy, opioids).". Responses were averaged to create a mean score. Higher scores indicate the participant is more willing to be a passenger in a car with an impaired driver.

    Time frame: Baseline, 6 month follow-up, and 12 month follow-up

06

Results

Posted Jun 29, 2023

Participant flow

Parent-teen dyads were recruited from a nationally representative predetermined Web panel (KnowledgePanel, KP) maintained by the consumer company Ipsos. KP members were randomly selected through probability-based sampling of addresses from the U.S. Postal Services' Delivery Sequence File which covers approximately 97% of U.S. households. Only individuals who were sampled through these probability-based techniques were eligible to participate.

Participant flow — Overall Study
MilestoneMADD MaterialsSurgeon General MaterialsActive Control
Started393393390
T2 (30 -days post-baseline)331328342
T3 (6-months post-baseline)315318319
T4 (12-months post-baseline)296305305
Completed296305305
Not completed978885

Outcome measures

PrimaryTypical Weekend Drinking (DDQ)

Typical weekend drinking was assessed using the Daily Drinking Questionnaire (DDQ; Collins et al., 1985), which asked teens to indicate the number of drinks they consumed on a typical Friday and Saturday during the past 6 months. These two items were summed to create the number of typical weekend drinks. Higher scores indicate the teen consumed a higher number of drinks on a typical weekend.

Time frame:
Baseline, 6 month follow-up, and 12 month follow-up
Reported as:
Mean · units on a scale
Typical Weekend Drinking (DDQ)
units on a scaleMADD MaterialsSurgeon General MaterialsActive Control
Typical Weekend Drinking (DDQ)0.53 ± 1.560.53 ± 1.570.38 ± 1.23
Statistical analysis
  • MADD Materials vs Surgeon General Materials vs Active Control · Tukey's Post-Hoc · p = >0.05 · Mean difference (final values): 0.17Estimation parameter used to determine significance between mean values in MADD, SG, and AC group.
PrimaryDeclining to Ride With Impaired Drivers

Declining riding with impaired drivers was assessed with two items adapted from Hultgren et al (2018). Teens were asked to indicate the number of times they declined a ride from a driver that consumed alcohol and the number of times they declined a ride from a driver that consumed any drug other than alcohol (e.g., marijuana, opioids) in the past 6 months. Responses were summed to indicate the number of times they declined rides from impaired drivers in the past 6 months. Higher scores indicate the participant declined more rides from impaired drivers.

Time frame:
T4 (12-months post-baseline)
Reported as:
Mean · units on a scale
Declining to Ride With Impaired Drivers
units on a scaleMADD MaterialsSurgeon General MaterialsActive Control
Declining to Ride With Impaired Drivers0.61 ± 1.560.56 ± 1.380.31 ± 0.99
Statistical analysis
  • MADD Materials vs Surgeon General Materials vs Active Control · Tukey's Post-Hoc · p = <0.01 · Mean difference (final values): 0.16Estimation parameter used to determine significance between mean values in MADD, SG, and AC group.
SecondaryWillingness to Ride in a Car With an Impaired Driver

Willingness to ride in a car with an impaired driver was assessed with two items adapted from Hultgren et al. (2018). Teens responded using a 7-point scale that ranged from (0) Strongly disagree to (6) Strongly agree on their level of agreement to the following statements, "I am willing to be a passenger in a vehicle when the driver has consumed alcohol." and "I am willing to be a passenger in a vehicle when the driver has consumed any drug other than alcohol (e.g., marijuana, ecstasy, opioids).". Responses were averaged to create a mean score. Higher scores indicate the participant is more willing to be a passenger in a car with an impaired driver.

Time frame:
Baseline, 6 month follow-up, and 12 month follow-up
Reported as:
Mean · units on a scale
Willingness to Ride in a Car With an Impaired Driver
units on a scaleMADD MaterialsSurgeon General MaterialsActive Control
Willingness to Ride in a Car With an Impaired Driver1.22 ± 0.031.22 ± 0.031.22 ± 0.03
Statistical analysis
  • MADD Materials vs Surgeon General Materials vs Active Control · Tukey's Post-Hoc · p = >0.01 · Mean difference (final values): 0.06Estimation parameter used to determine significance between mean values in MADD, SG, and AC group.

Adverse events

Collected over 1 year. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
MADD Materials0/393 (0%)0/393 (0%)0/393 (0%)
Surgeon General Materials0/393 (0%)0/393 (0%)0/393 (0%)
Active Control0/390 (0%)0/390 (0%)0/390 (0%)

Baseline characteristics

Age, Categorical
Age, Categorical(Participants)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Teen Participants — <=18 years3933933901176
Teen Participants — Between 18 and 65 years0000
Teen Participants — >=65 years0000
Parent Participants — <=18 years0000
Parent Participants — Between 18 and 65 years3853873821154
Parent Participants — >=65 years86822
Age, Continuous
Age, Continuous(years)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Teen Participants16.29 ± 1.0916.37 ± 1.1116.33 ± 1.0916.33 ± 1.09
Parent Participants46.58 ± 7.4446.90 ± 7.7646.77 ± 7.6546.75 ± 7.61
Sex: Female, Male
Sex: Female, Male(Participants)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Teen Participants — Female179197203579
Teen Participants — Male214196187597
Parent Participants — Female223213204640
Parent Participants — Male170180186536
Ethnicity (NIH/OMB)
Ethnicity (NIH/OMB)(Participants)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Teen Participants — Hispanic or Latino11510398316
Teen Participants — Not Hispanic or Latino278290292860
Teen Participants — Unknown or Not Reported0000
Parent Participants — Hispanic or Latino1069790293
Parent Participants — Not Hispanic or Latino287296300883
Parent Participants — Unknown or Not Reported0000
Race (NIH/OMB)
Race (NIH/OMB)(Participants)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Teen Participants — American Indian or Alaska Native6028
Teen Participants — Asian15121340
Teen Participants — Native Hawaiian or Other Pacific Islander1113
Teen Participants — Black or African American323533100
Teen Participants — White288305300893
Teen Participants — More than one race31233084
Teen Participants — Unknown or Not Reported20171148
Parent Participants — American Indian or Alaska Native52714
Parent Participants — Asian1391234
Parent Participants — Native Hawaiian or Other Pacific Islander1012
Parent Participants — Black or African American323139102
Parent Participants — White302313305920
Parent Participants — More than one race19181148
Parent Participants — Unknown or Not Reported21201556
Teen Typical Weekly Drinking (DDQ)
Teen Typical Weekly Drinking (DDQ)(units on a scale)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Mean0.23 ± 0.970.20 ± 0.850.23 ± 1.010.22 ± 0.94
Teen Riding with Impaired Drivers Measures
Teen Riding with Impaired Drivers Measures(units on a scale)MADD MaterialsSurgeon General MaterialsActive ControlTotal
Impaired driving0.16 ± 0.870.10 ± 0.680.08 ± 0.550.11 ± 0.71
Declining to ride with impaired driver0.51 ± 1.330.44 ± 1.320.37 ± 1.170.44 ± 1.28
Passenger in car with impaired driver0.57 ± 2.00.52 ± 1.820.46 ± 1.720.52 ± 1.85
07

Study locations

1 site
  • Penn State University
    University Park, Pennsylvania 16802, United States
08

References and documents

Study documents

  • Protocol and statistical analysis plan · Jun 8, 2023

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Registry details

Key details

Study ID
NCT03506880
Lead sponsor
Penn State University
Collaborators
National Institutes of Health (NIH), National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Responsible party
Robert Turrisi (Professor of Biobehavioral Health, Penn State University) — Principal investigator
First posted
Apr 24, 2018
Start date
Nov 17, 2017
Primary completion
Apr 30, 2022
Completion
Apr 30, 2022
Results posted
Jun 29, 2023
Last update
Jun 29, 2023

Study contacts

Robert Turrisi, Ph.D.
principal investigator · Penn State University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
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