An observational study in Pregnancy Related and Physical Activity, sponsored by Pennington Biomedical Research Center. Completed at 1 site in United States. Open to female participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-09-27.
Sponsored by Pennington Biomedical Research Center · Observational
Among 39 studies in Motor Activity by Pennington Biomedical Research Center — 2 open to participants now, 3 under way, none of them phase 3. Motor Activity · Pennington Biomedical Research Center.
Among the 39 studies in Motor Activity by Pennington Biomedical Research Center, this one is the 11th largest by enrollment of the 12 observational ones that give a count, is one of 5 that started in 2018, is one of 12 observational ones, and was the 29th registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
Browse Motor Activity studies →2 of the 39 studies in Motor Activity by Pennington Biomedical Research Center are open now, in 1 country. Recruiting first, the newest first:
Pennington Biomedical Research Center · Sites in United States
Pennington Biomedical Research Center · Sites in United States
By country, each count listing its studies:
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 18 Years to 40 Years · female · healthy volunteers too.
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39 studies; the count open now beside each. This study's row is marked.
First in 2007; this study’s year is marked. 5 started in 2018.
This study's enrollment of 20 is below the median of 98 across 1,235 observational studies indexed under Motor Activity.
Median enrollment 41 across the 27 interventional studies, 57 across the 12 observational. Of the 36 that completed or were terminated, 13 (36%) have results posted.
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Pennington Biomedical Research Center is the lead sponsor of 284 studies on the registry; 31 are open to participants now.
None of the studies under way reaches primary completion within a year.
Among the 39 studies in Motor Activity by Pennington Biomedical Research Center, from their registry updates:
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This Pilot \& Feasibility study will test the hypothesis that pregnant women who are more active will have better functioning mitochondria in vivo (higher ATPmax, via 31P-MRS), which will be positively related to maternal and infant mitochondrial function in vitro (higher oxygen consumption rates in primary myotubes and umbilical cord derived mesenchymal stem cells, respectively). Twenty pregnant women (10 active and 10 sedentary) will be recruited in the first trimester of pregnancy determined from self-reported physical activity and assessment by activity monitors. Placental biospecimens will be collected during delivery for other molecular mitochondrial analyses.
Healthy women that are classified as either physically active or sedentary in early pregnancy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Physically active will be defined by self-report and confirmed by step counts \>8,000 per day from activity monitoring.
Behavioral: Active
Sedentary lifestyle will be defined by self-report and confirmed by step counts \<5,000 per day from activity monitoring.
Behavioral: Sedentary
No behavioral intervention included but the exposure is level of physical activity. Individuals in the Active group will be categorized by their own routine physical activity levels.
No behavioral intervention included but the exposure is level of physical activity. Individuals in the Sedentary group will be categorized by their own routine physical activity levels.
Infant in vitro mitochondrial capacity (by oxygen consumption rate)
Infant in vitro mitochondrial capacity measured by oxygen consumption rates in umbilical cord derived mesenchymal stem cells at delivery
Time frame: 1 day
Relationship between in vivo mitochondrial capacity and infant in vitro mitochondrial capacity (by oxygen consumption rates)
Relationship between in vivo and in vitro mitochondrial capacity will be measured with in vivo mitochondrial capacity measured by 31P-MRS and infant in vitro mitochondrial capacity measured by oxygen consumption rates in umbilical cord derived mesenchymal stem cells
Time frame: About 20 weeks
Relationship between in vivo mitochondrial capacity and maternal in vitro mitochondrial capacity (by oxygen consumption rate)
Relationship between in vivo and in vitro mitochondrial capacity will be measured with in vivo mitochondrial capacity measured by 31P-MRS and maternal in vitro mitochondrial capacity measured by oxygen consumption rates in maternal primary myotubes
Time frame: About 15 weeks
Plan to share: No
Ran from Mar 2018 to primary completion in Feb 2020, 22 months.
Of 490 non-industry observational studies under Motor Activity, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 48. This study's 22 months is close to that.
Counting every sponsor, half of 500 studies reached it within 22 months; a quarter within 8 and three quarters within 48.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2022. You cannot join it, but the record below documents what was studied.
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