An observational study in Non-Communicable Disease, sponsored by Memorial Sloan Kettering Cancer Center. Active, not recruiting at 14 sites in 2 countries. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-18.
Sponsored by Memorial Sloan Kettering Cancer Center · Observational
This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison.
Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.
144 studies on the registry are indexed under Noncommunicable Diseases; 55 are open to participants now.
This study's enrollment of 6,990 is above the median of 1,674 across 48 observational studies indexed under Noncommunicable Diseases.
Browse Noncommunicable Diseases studies →Memorial Sloan Kettering Cancer Center is the lead sponsor of 1,964 studies on the registry; 327 are open to participants now.
Of its 135 completed or terminated interventional studies of FDA-regulated products, 71 (53%) have results posted.
Counted across the registry records on this site, refreshed daily.
Participants will be accrued in medical clinics in Africa as determined by the local investigators and local research staff.
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Exclusion Criteria:
This protocol will entail prospective collection of data on healthy participants and participants diagnosed with NCDs managed at collaborating institutions in SSA. Information to be obtained includes socio-demographic data, risk factors, disease-specific data, investigation and treatment details, as well as findings during follow-up. Particular reference will be made to outcome measures such as local and distant recurrence, survival and mortality. Follow-up data will be updated during clinic visits and also via phone calls.
Behavioral: Questionnaire forms · Other: Bio-specimen samples
The questionnaires will include information such as socio-demographic data, risk factors, disease specific data, investigation and treatment details as well as findings during followup. Particular reference will be made to outcome measures such as local and distant recurrence, survival and mortality.
Samples can include tissue, blood, urine, saliva, hair and nail clipping.
# of patients that develope non-communicable diseases in Africa
Time frame: 5 years
Started Mar 2018 (actual). Primary completion is estimated for Mar 2027, 108 months after the start.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Memorial Sloan Kettering Cancer Center →