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WithdrawnNCT03459651Updated May 9, 2022

Effect of Turner Syndrome on Number Sense

An interventional study of ANS training in Turner Syndrome, sponsored by Stanford University. Withdrawn at 1 site in United States. Open to female participants aged 6 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-09.

Sponsored by Stanford University · Not applicable, Interventional, and Treatment

Why this study was withdrawn
Principal Investigator elected to end the study.
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Not applicable
Ages
6 Years to 40 Years
Sex
Female
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Study summary

This study evaluates approximate number sense (ANS) in children, adolescents, and adult women with Turner syndrome compared to age-matched healthy peers. One primary aim of this project is to assess the effectiveness of an online ANS training tool in enhancing complex mathematics ability. Participants will undergo weekly training sessions in their own home. Half of the participants will complete 2 training sessions a week for 8 weeks, and the second half will complete 1 training session for 8 weeks.

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Conditions studied

  • Turner Syndrome

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Keywords

  • numeracy
  • number sense
03

In context

Turner Syndrome

119 studies on the registry are indexed under Turner Syndrome; 33 are open to participants now.

Browse Turner Syndrome studies →

Lead sponsor

Stanford University is the lead sponsor of 2,161 studies on the registry; 428 are open to participants now.

Of its 268 completed or terminated interventional studies of FDA-regulated products, 207 (77%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
6 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Children, adolescents, and adult women with Turner syndrome.
  • Healthy controls.
  • Normal or corrected to normal vision.

Exclusion criteria

Exclusion Criteria:

  • Major psychiatric or developmental disorder (e.g., bipolar disorder, major depression, psychotic disorders, intellectual disability, autism spectrum disorder).
  • Chemical dependency
  • Currently taking the following medications: antidepressant, antipsychotic, and anti-seizures drugs.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    ANS training

    Behavioral: ANS training

Interventions

  • BehavioralANS training

    In-home computer-based ANS training

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What researchers measure

Primary outcomes

  1. Single and multiple-operand addition and subtraction accuracy

    Task accuracy calculated as the percentage of trials answered correctly.

    Time frame: 8 weeks

  2. Single and multiple-operand addition and subtraction response time

    Average amount of time, in seconds, required to answer each question on the task.

    Time frame: 8 weeks

07

Study locations

1 site
  • Center for Interdisciplinary Brain Sciences Research
    Stanford, California 94305, United States
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References and documents

Individual participant data

Plan to share: Undecided — De-identified individual participant data for the primary outcome measures may be made available upon reasonable request.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 9, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03459651
Responsible party
Joseph Michael Baker (Instructor, Stanford University) — Principal investigator
First posted
Mar 9, 2018
Start date
Apr 1, 2022
Primary completion
Apr 2, 2022
Completion
Apr 2, 2022
Last update
May 9, 2022

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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