An interventional study of FTIR spectroscopy in Epiretinal Membrane and Macular Hole, sponsored by Vienna Institute for Research in Ocular Surgery. Completed at 1 site in Austria. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-09-29.
Sponsored by Vienna Institute for Research in Ocular Surgery · Not applicable, Interventional, and Diagnostic
Among 10 studies in Epiretinal Membrane by Vienna Institute for Research in Ocular Surgery — 1 open to participants now, 2 under way, none of them phase 3. Epiretinal Membrane · Vienna Institute for Research in Ocular Surgery.
Among the 10 studies in Epiretinal Membrane by Vienna Institute for Research in Ocular Surgery, this one is one of 2 that started in 2017, is one of 8 with no phase, and was the 3rd registered.
130 studies on the registry are indexed under Epiretinal Membrane; 18 are open to participants now.
This study's enrollment of 50 is close to the median of 51 across 79 interventional studies indexed under Epiretinal Membrane.
Browse Epiretinal Membrane studies →1 of the 10 studies in Epiretinal Membrane by Vienna Institute for Research in Ocular Surgery is open now, in 1 country. Each count lists the studies.
Of the 11 Epiretinal Membrane studies recruiting now, 9 (82%) set no upper age limit and 0 (0%) stop at 75 or younger; 2 take children under 18; 2 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →10 studies; the count open now beside each. This study's row is marked.
First in 2015; this study’s year is marked. 2 started in 2017.
Median enrollment 46 across the 8 interventional studies, 106 across the 2 observational. Of the 7 that completed or were terminated, 0 (0%) have results posted.
Vienna Institute for Research in Ocular Surgery is the lead sponsor of 65 studies on the registry; 8 are open to participants now.
None of the studies under way reaches primary completion within a year.
Among the 10 studies in Epiretinal Membrane by Vienna Institute for Research in Ocular Surgery, from their registry updates:
Nothing recorded among them since 2026-09-25.
Epiretinal membranes (ERM) are disorders leading to vision loss and metamorphopsia. Vitrectomy with membrane peeling has developed to be the gold-standard in treatment of ERM. ERM can be well visualized with spectral domain optical coherence tomography (SD-OCT).
The aim of the study is to examine ERM and internal limiting membranes (ILM) exzised during routine macular surgery with fourier transformed infrared spectroscopy (FTIR) and compare results to optic coherence tomography (OCT) findings.
Purpose of the present study is to analyse components of ERM and ILM, giving hints for the origin of cells producing ERM. In contrast to electron microscopy, FTIR spectroscopy does not need any chemical fixation of the membranes and therefore structure of components of ERM and ILM are not changed by fixation.
In total, 20 eyes with idiopathic ERM, 10 eyes with lamellar macular hole, 10 eyes with full thickness macular hole and 10 eyes with diabetic ERM will be examined. To our knowledge there are no previous reports about FTIR spectroscopy of ERM and ILM, therefore the study will be performed as an exploratory pilot study.
Inclusion Criteria:
Exclusion Criteria: - Macular edema due to other reasons than ERM
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
all excised membranes are examined with FTIR spectroscopy
Device: FTIR spectroscopy
FTIR spectroscopy examines collagen fibers in the excised membranes
collagen
occurrence of different types of collagen fibres in the excised membranes
Time frame: 3 months
Ran from Jan 2017 to primary completion in Jun 2019, 29 months.
Of 30 interventional studies with no phase under Epiretinal Membrane, half reached primary completion within 29 months of starting (the median), counting those still running; a quarter within 15 and three quarters within 90. This study's 29 months is close to that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.
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Vienna Institute for Research in Ocular Surgery