An observational study in High Myopia, sponsored by Shanghai Eye Disease Prevention and Treatment Center. Status unknown at 1 site in China. Open to participants aged 18 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-02-26.
Sponsored by Shanghai Eye Disease Prevention and Treatment Center · Observational
High myopia retinopathy has become the first cause of irreversible blindness and severe visual impairment in Chinese adults, in order to avoid the blind and visual impairment caused by high myopia retinopathy, it is very necessary to research the mechanism of early visual impairment to prevent and control damages. Our recent research found that the decreasing of macular retina vascular density and subfoveal choroidal thickness, the increasing of Beta Zone area in optic atrophy and the rising of glycosylated hemoglobin in high myopia patients were significantly related to visual impairment, which suggested that the source of visual impairment was the abnormal structure changes surrounding optic and fovea, but so far there is no related study. We will conduct a 5 years prospective cohort study in the population of 2420 high myopia and controls which have established in college student population, working population and aged more than 50 years old population, using the latest OCT-A and SS-OCT to measure macular retina vascular density, subfoveal choroidal thickness, Beta Zone area in optic atrophy, combined with the semiparametric mixed effects model, we will analysis the prediction index between fundus structure parameters, blood biochemical index and individual characteristics prediction to explore the public health management mode of early prevention and treatment during high myopia population.
360 studies on the registry are indexed under Vision Disorders; 84 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 126 across 97 observational studies indexed under Vision Disorders.
Browse Vision Disorders studies →Shanghai Eye Disease Prevention and Treatment Center is the lead sponsor of 66 studies on the registry; 30 are open to participants now.
Counted across the registry records on this site, refreshed daily.
college student population; working population; aged more than 50 years old population.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Retina Vessel Density (RVD)
RVD is calculated both the macular and peripapillary area.
Time frame: December 31, 2016
tilted optic disc
A tilted optic disc was defined as the tilt ratios ≤0.80.
Time frame: December 31, 2016
β-zone PPA
The β-zone PPA area (an inner crescent of chorioretinal atrophy with good visibility of the large choroidal vessels and the sclera) was determined as the total number of pixels using the ImageJ software in a circumferential pattern.
Time frame: December 31, 2018
glycosylated hemoglobin
This test measures the average blood sugar control for the previous three months or so.
Time frame: December 31, 2020
Plan to share: Undecided
No publications or documents are linked to this record.
Started Jan 2016 (actual). Primary completion is estimated for Dec 2019, 47 months after the start.
Of 51 non-industry observational studies under Vision Disorders, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 42. This study's planned 47 months is above that.
Counting every sponsor, half of 58 studies reached it within 23 months; a quarter within 12 and three quarters within 52.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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Shanghai Eye Disease Prevention and Treatment Center