An observational study in Aortic Aneurysm, Abdominal, sponsored by Mayo Clinic. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-02-23.
Sponsored by Mayo Clinic · Observational
Among 122 studies in Aortic Aneurysm, Abdominal with a site in United States — 28 open to participants now, 35 under way, 1 of them phase 3. Aortic Aneurysm, Abdominal · United States.
Among the 122 studies in Aortic Aneurysm, Abdominal with a site in United States, this one is the 22nd largest by planned enrollment of the 32 observational ones, is one of 7 that started in 2021, is one of 32 observational ones, reaches primary completion later than 9 of the 34 other live ones, and was the 88th registered.
467 studies on the registry are indexed under Aortic Aneurysm, Abdominal; 99 are open to participants now.
This study's planned enrollment of 150 is close to the median of 165 across 217 observational studies indexed under Aortic Aneurysm, Abdominal.
Browse Aortic Aneurysm, Abdominal studies →28 of the 122 studies in Aortic Aneurysm, Abdominal with a site in United States are open now, in 12 countries. Each count lists the studies.
Of the 66 Aortic Aneurysm, Abdominal studies recruiting now, 52 (79%) set no upper age limit and 3 (5%) stop at 75 or younger; 2 take children under 18; 8 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →122 studies; the count open now beside each. This study's row is marked.
First in 1998; this study’s year is marked. 7 started in 2021.
Median enrollment 94 across the 85 interventional studies, 210 across the 32 observational. Of the 73 that completed or were terminated, 39 (53%) have results posted.
63 of 122 have an industry lead sponsor. The 10 most frequent:
Mayo Clinic is the lead sponsor of 3,269 studies on the registry; 672 are open to participants now.
Of its 452 completed or terminated interventional studies of FDA-regulated products, 321 (71%) have results posted.
Mayo Clinic has 4 studies filed under Aortic Aneurysm, Abdominal — fewer than ten, so there is no comparison to draw.
10 of the studies in Aortic Aneurysm, Abdominal with a site in United States that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT04875429Cook Research IncorporatedZenith® Fenestrated+ Clinical Study | 2026-11 |
| NCT03446287Mayo ClinicClinical Outcomes of Patients Treated With Open Surgical Repair for Complex Aortic Aneurysms | 2026-12 |
| NCT05004051ViTAA Medical SolutionsViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA | 2026-12-31 |
| NCT07473102Washington University School of MedicinePET Imaging of MMP Activation in AAA: Clinical Component | 2027-03-31 |
| NCT06990048EndologixThe Long-Term EVAR Assessment and Follow-Up (LEAF) Study for the AFX2 System | 2027-05 |
Among the 122 studies in Aortic Aneurysm, Abdominal with a site in United States, from their registry updates:
This is a prospective, non-randomized, single center, data collection study of patients treated with open surgical repair (OR) for complex aortic aneurysms (CAAs).
Patients in need of OR for CAAs will be placed in this prospective, non-randomized, single center, data collection study. Choice of the prosthetic graft and configuration will be based on surgeon's preference and extent of the disease. OR will be performed by vascular surgeons at Mayo Clinic, Rochester, assuming no difference in surgical techniques.
Demographics, clinical presentation, preoperative clinical and imaging assessment, intraoperative information, length of ICU stay and hospitalization, early and late mortality, major adverse events (MAEs), reintervention, rupture and QoL at different postoperative time points (4 months, 1 year, 3 years and 5 years) will be recorded according to well-designed case report forms (CRFs) and SF-36 form. Follow-up information will be obtained from office visits or mailing questionnaires (SF-36 form and CAA-specific questionnaire).
Patients will be asked to fill out the SF-36 forms preoperatively, and along with the CAA-specific questionnaire at 4 months, 1 year, 3 years and 5 years post-operatively. Physician assistants or study coordinators will interview all patients prior to treatment (during office evaluation). The follow-up assessments will be conducted by questionnaires (SF-36 and CAA-specific questionnaire) and office visits as well. If no response in 6 weeks after sending out questionnaires at each time point, telephone interview will be followed.
Patients undergoing open repair (OR) for complex aortic aneurysms (CAAs) at Mayo Clinic, Rochester, Minnesota will be enrolled.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Patients undergoing elective, emergent or urgent OR for CAAs, including:
Exclusion Criteria:
Change in health-related quality of life after open repair as measured by the Short-Form General Health Survey (SF-36)
The SF-36 consists of 8 sub-scales which are additionally summarized into 2 summary components (physical and mental). The subscales and the summary scales both range from 0 to 100, with (0 = worst imaginable, 100 = best imaginable).
Time frame: baseline, 5 years post repair
Plan to share: No
Started Jul 2021 (actual). Primary completion is estimated for Dec 2026, 65 months after the start.
Of 67 non-industry observational studies under Aortic Aneurysm, Abdominal, half reached primary completion within 48 months of starting (the median), counting those still running; a quarter within 22 and three quarters within 83. This study's planned 65 months is above that.
Counting every sponsor, half of 91 studies reached it within 48 months; a quarter within 24 and three quarters within 83.
How these figures are worked out, and which studies are left out of them.
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