CClinicalTrials.gg
Status unknownNCT03445091Updated Mar 2, 2018

Study to Evaluate Impact SANKOM Patent Socks in Patients With CVI

An interventional study of SANKOM Patent Socks in Chronic Venous Insufficiency, sponsored by Sankom SA. Status unknown at 2 sites in Ukraine. Open to participants aged 35 Years to 65 Years. Per ClinicalTrials.gov, last updated 2018-03-02.

Sponsored by Sankom SA · Not applicable, Interventional, and Supportive care

The sponsor has not verified this record recently (last verified Feb 2018), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
35 Years to 65 Years
Sex
All
01

Study summary

Clinical study to evaluate impact on quality of life in patients with Chronic Venous Insufficiency during 4 weeks period of using SANKOM® Patent Socks

Read the detailed description

Despite the application of compression stockings looks simple, it must be remembered that inappropriately worn stockings have the potential to cause certain problems. Unevenly distributed and excess pressure may break the skin, especially in older, malnourished patients and those with thin, brittle skin.

Although an extreme case, it highlights the importance of careful assessment, application, and monitoring of compression stockings.

Typically, the stockings are safe and wearing them results in few or no complications, provided they're worn smoothly against the leg, without any folds. But some groups of people should avoid them, including those with peripheral neuropathy or any other condition that impacts skin sensation; a history of a peripheral arterial bypass grafting; peripheral artery disease; skin infection; dermatitis with oozing or fragile skin; massive leg swelling; or pulmonary edema from congestive heart failure. Each of these conditions presents a different series of risks. For example, for people with peripheral artery disease, stockings can worsen oxygen delivery in arteries with impaired blood flow. People who have sensory problems, such as those with peripheral neuropathy, may not feel when a compression stocking is too tight, which could impede circulation. And certain skin conditions or infections may worsen with a compression stocking covering and pressing on the area.

In general, if subject has any medical condition, he/she should talk with health care professional before using compression stockings to see if they are good candidate for them.

Since probability of side/adverse effects from IP use is considered as very low vs of high probability of expected positive effects.

Study Purpose and Design Multi-center, observational open label study aimed to evaluate an impact on quality of life in Chronic Venous Insufficiency patients using SANKOM® Patent Socks during 4 weeks

This study will involve a maximum of 30 subjects. Subjects will be followed through outpatient's observation.

Primary Objective

Improvement of QoL by scores of:

  • Aberdeen Varicose Veins Questionnaire (AVVQ)
  • CIVIQ-2 Venous Quality of Life Questionnaire

Secondary Objectives

Secondary Endpoints are:

  • Improvement of US-examination picture
  • Improvement of QoL by Subject's questionnaire
02

Conditions studied

  • Chronic Venous Insufficiency

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Keywords

  • compression socks
  • venous insufficiency
  • compression stockings
  • compression
  • compression therapy
03

Who can participate

Ages eligible
35 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Subject is informed and given ample time and opportunity to think about his/her participation and has given his/her written informed consent before any procedure;
  2. Subject is male or female, 35-65 years of age;
  3. Subject with chronic venous insufficiency CEAP (C1, C2);
  4. Subject can speak and understand Ukrainian or Russian language.

Exclusion criteria

Exclusion Criteria:

  1. Subject participated in any clinical study (drug or device) within 6 months prior to the screening;
  2. Subject unable to wear compression stockings;
  3. Subject using other compression therapy.
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Patients using investigational product

    Open-label use of SANKOM Patent Socks

    Device: SANKOM Patent Socks

Interventions

  • DeviceSANKOM Patent Socks

    Using compression socks to ease symptoms of patients with chronic venous insufficiency

    Also known as: gradient compression socks

05

What researchers measure

Primary outcomes

  1. Improvement of health status in varicose veins patients

    By mean of growing Aberdeen Varicose Veins Questionnaire score (total range 0 - 60). The higher values represent a better outcome.

    Time frame: 4 weeks

Secondary outcomes

  1. Improvement of Quality of Life

    Growing of scrore of Quality of life questionnaire in Chronic Lower Limb Venous Insufficiency (CIVIQ-2) is expected

    Time frame: 4 weeks

  2. Improvement of ultara sound examination measures

    Speed of venous blood flow of lower limbs is measured

    Time frame: 4 weeks

  3. Improvement of subject's self-assessment questionnaire

    Subjective assessment of visual analog scale

    Time frame: 4 weeks

06

Study locations

2 sites
  • Kyiv City Clinical Hospital No 6
    Kyiv, 03126, Ukraine
  • Medical Consulting Center of Pechersk District
    Kyiv, Ukraine
07

References and documents

Individual participant data

Plan to share: No — There is no plan to share the data yet.

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03445091
Lead sponsor
Sankom SA
Collaborators
InterMedService SA, Pharmaxi LLC
Responsible party
Sponsor
First posted
Feb 26, 2018
Start date
Feb 5, 2018
Primary completion
Apr 1, 2018 (estimated)
Completion
Apr 1, 2018 (estimated)
Last update
Mar 2, 2018

Study contacts

Serge M Mazourik, MD
study chair · Intermedservice

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.

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