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CompletedNCT03444597Suprasorb®CUpdated Feb 19, 2020

Post-Market Clinical-Follow-Up Study of Suprasorb® C Collagen Wound Dressing

An observational study in Venous or Mixed Leg Ulcers, sponsored by Lohmann & Rauscher. Completed at 1 site in France. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2020-02-19.

Sponsored by Lohmann & Rauscher · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
111
Ages
18 Years to 85 Years
Sex
All
01

Study summary

Post-Market Clinical-Follow-Up Study of Suprasorb® C collagen wound dressing

Read the detailed description

Prospective, uncontrolled multi-center, observational cohort study. The objectives of the PMCF study are confirmation of the performance, and to collect additional safety data regarding expected adverse events and to detect potential unexpected adverse events associated with use of Suprasorb®C under the conditions of routine use.

Suprasorb® C collagen wound dressing is a certified medical device (manufacturer: Lohmann \& Rauscher International GmbH \& Co. KG). The product has been marketed in the EU since 1983 as Opragen® (medicinal product), since 1995 as the medical device Opraskin® and since 2001 under the name Suprasorb C (medical device).

Suprasorb® C is intended to be used as a wound dressing for the support of wound healing or wound area reduction.

Participating Centers: 40 study nurses will participate to the PMCF Study Duration: 24 months Cohort size: 110 patients Follow-up: 8 weeks

02

Conditions studied

  • Venous or Mixed Leg Ulcers

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03

Who can participate

Ages eligible
18 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The patient population is patient with venous or mixed leg ulcers

Inclusion criteria

  • Patient over 18 years of age and under 85 years of age
  • Patient suffering from confirmed venous or mixed vascular leg ulcers
  • Stagnating wound conditions, i.e. exudation phase > 2 months, not responding to traditional dressing and standard treatment (standard treatment is a clear definition and for venous ulcers compression should be included)
  • Target ulcers between 2 cm and 10 cm in the largest diameter
  • Written confirmation from the study nurse that the patient was informed, orally agreed to participate and to comply with study treatment and planned visits

Exclusion criteria

Exclusion Criteria:

Use of Suprasorb® C collagen wound dressing is contraindicated according to the current IFU:

  • Clinically infected areas
  • Presence of known allergies to one or several of its components.

In addition following patients shall not be included into this study:

  • Patient not covered by health insurance/social security
  • Patient suffering serious life threatening disease
  • Pregnant or breastfeeding women
  • Minor patient, protected adult, person without liberty
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
111 participants (actual)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Progression of healing after application of Suprasorb® C collagen wound dressing is used as parameter for performance evaluation

    Progression of healing after application of Suprasorb® C collagen

    Time frame: Progression of healing is assessed at 8 weeks

Secondary outcomes

  1. Frequency and severity of adverse events

    Frequency and severity of adverse events, incidences, as well as known risk and side effects, i.e. wound infection, side effects in the group of allergic disorders, pain, and maceration

    Time frame: Frequency and severity is assessed up to 8 weeks

06

Study locations

1 site
  • RCTs
    Lyon, 69002, France
07

Registry details

Key details

Study ID
NCT03444597
Lead sponsor
Lohmann & Rauscher
Responsible party
Sponsor
First posted
Feb 23, 2018
Start date
Jan 24, 2018
Primary completion
Jan 23, 2020
Completion
Jan 23, 2020
Last update
Feb 19, 2020

Study contacts

Daria TROFIMENKO
study director · Lohmann and Rauscher

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2020. You cannot join it, but the record below documents what was studied.

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