ClinicalTrials.gg
CompletedNCT03444012Updated Aug 7, 2020

ADHERE-S (NIS Brilique)

An observational study in ACS (Acute Coronary Syndrome), sponsored by AstraZeneca. Completed at 9 sites in Serbia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-08-07.

Sponsored by AstraZeneca · Observational

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Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
269
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-15

Among 36 studies in Acute Coronary Syndrome by AstraZeneca — none open to participants now, none under way, none of them phase 3. Acute Coronary Syndrome · AstraZeneca.

Enrollment
22nd of 24
269 · median 1,036
Started
2018
the only one that year
Observational
24 of 36
none open now
Registered
36th of 36
by date

Among the 36 studies in Acute Coronary Syndrome by AstraZeneca, this one is the 22nd largest by enrollment of the 24 observational ones that give a count, is the only one that started in 2018, is one of 24 observational ones, and was the 36th registered.

Acute Coronary Syndrome

1,490 studies on the registry are indexed under Acute Coronary Syndrome; 272 are open to participants now.

Browse Acute Coronary Syndrome studies →

Open to participants now

None of the 36 studies in Acute Coronary Syndrome by AstraZeneca is open now. The open studies under Acute Coronary Syndrome, anywhere →

Who these studies take

Of the 196 Acute Coronary Syndrome studies recruiting now, 145 (74%) set no upper age limit and 19 (10%) stop at 75 or younger; 15 take children under 18; 15 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

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Download CSVNarrow it in search →With an account: the 36 studies in Acute Coronary Syndrome by AstraZeneca as a file.
02

Study summary

noninterventional study investigating persistence and adherence on ticagrelor in ACS patients in Serbia

03

Conditions studied

  • ACS (Acute Coronary Syndrome)
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult ACS patients

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • ≥ 18 years of age
  • diagnosed with ACS - STEMI or NSTEMI or unstable angina, invasively or non-invasively treated
  • Patients already on treatment with ticagrelor at least for 1 month and no longer than 3 months prior to study initiation. Enrolment in this study must not be trigger for ticagrelor initiation.
  • read and signed the Form

Exclusion criteria

Exclusion Criteria:

Any as per approved SmPC of Brilique

  • Patients with life-threatening conditions which could disable patients to comply with scheduled visits and/or not able to fill in the patient questionnaires.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorized to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
269 participants (actual)
Patient registry
No

Interventions

06

What researchers measure

Primary outcomes

  1. duration (number of days) on ticagrelor therapy in patients with acute coronary syndrome

    Time frame: 1 year (12 months)

07

Study locations

9 sites
  • CHC Bezanijska Kosa
    Belgrade, Serbia
  • CHC Zemun
    Belgrade, Serbia
  • CHC Zvezdara
    Belgrade, Serbia
  • Clinical Center of Serbia
    Belgrade, Serbia
  • Institute for cardiovascular diseases, Dedinje
    Belgrade, Serbia
  • Medical Military Academy
    Belgrade, Serbia
  • Clinical Center Kragujevac
    Kragujevac, Serbia
  • Clinical Center Nis
    Nis, Serbia
  • Institute for cardiovascular diseases of Vojvodina
    Sremska Kamenica, Serbia
08

References and documents

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Mar 2018 to primary completion in Aug 2019, 17 months.

How these figures are worked out, and which studies are left out of them.

Registered
Feb 9, 2018
First posted
Feb 23, 2018
StartActual
Mar 5, 2018
Primary completionActual
Aug 13, 2019
CompletionActual
Aug 13, 2019
Last update
Aug 7, 2020
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 7, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03444012
Lead sponsor
AstraZeneca
Responsible party
Sponsor
First posted
Feb 23, 2018
Start date
Mar 5, 2018
Primary completion
Aug 13, 2019
Completion
Aug 13, 2019
Last update
Aug 7, 2020
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2020. You cannot join it, but the record below documents what was studied.

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Discussion

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